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Hepatitis C in a New Era: A Review of Current Therapies

机译:新时代丙型肝炎:对当前疗法的综述

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INTRODUCTION: The prevalence of chronic hepatitis C virus (HCV) infection has been estimated at between 1.2% and 1.7% in the adult global population, suggesting that 62 million to 89 million people are affected by the disease. In the United States, the estimated prevalence of chronic HCV infection was 2.7 million, based on survey data from 2003 to 2010; however, this estimate may understate the true prevalence because the survey did not include key high-risk populations, such as homeless and incarcerated individuals. The Centers for Disease Control and Prevention (CDC) currently estimates the number of chronically infected people in the U.S. to be 2,7 million to 3.9 million. In 2014, the cause of death for 19,659 U.S. residents was attributed in whole or in part to HCV. Total health care costs associated with HCV disease and its complications, excluding treatment expenses, were estimated to be $6.5 billion in 2011, with a projected increase to $9.1 billion by 2024. Treatment costs associated with HCV therapy have increased rapidly from $77 million in 2009 to $18.4 billion in 2015, with the approval of direct-acting antivirals (DAAs) driving those expenses.Long Island University, LIU Pharmacy (Arnold and Marie Schwartz College of Pharmacy and Health Sciences) in Brooklyn, New York.
机译:介绍:慢性丙型肝炎病毒(HCV)感染的患病率估计成人全球人口的1.2%和1.7%,表明6200万至8900万人受到疾病的影响。在美国,基于2003年至2010年的调查数据,慢性HCV感染的估计患病率为270万;然而,这种估计可能会低估真正的流行率,因为调查没有包括关键的高风险群体,例如无家可归者和被监禁的个人。疾病控制和预防中心(CDC)目前估计美国在美国的长期感染者数量为2,700万至390万。 2014年,19,659美国居民死亡的原因全部或部分归因于HCV。与HCV疾病相关的医疗保健成本及其并发症,不包括治疗费用,估计2011年的650亿美元,预计将增加到2024年的91亿美元。与2009年的7700万美元相关的治疗成本从7700万美元增加到迅速增加2015年的184亿美元,批准促进纽约布鲁克林的刘岛大学,刘氏岛大学,刘药房(阿诺德和玛丽施瓦茨学院)。

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