Feasibility Study of Portable X-ray Fluorescence (pXRF) for the Determination of Iodine in Pharmaceutical Products

摘要

A quick and accurate method for the determination of iodine in pharmaceutical products is critical for manufacturers to ensure product quality and to comply with the legal requirements as determined by authorities such as the Therapeutic Goods Administration (TGA) in Australia. As a noninvasive and nondestructive method of testing that requires little to no sample preparation, pXRF has been found to be one of the most efficient and economic analytical tools for elemental analysis in a wide range of applications. In this study, an approach using pXRF offers another option for the determination of iodine in multivitamin tablets, which is proving superiority for quality control on the production line.