Tocilizumab in giant cell arteritis. Observational, open-label multicenter study of 134 patients in clinical practice

Calderon-Goercke Monica; Loricera Javier; Aldasoro Vicente; Castaneda Santos; Villa Ignacio; Humbria Alicia; Moriano Clara; Romero-Yuste Susana; Narvaez Javier; Gomez-Arango Catalina; Perez-Pampin Eva; Melero Rafael; Becerra-Fernandez Elena; Revenga Marcelino; Alvarez-Rivas Noelia; Galisteo Caries; Sivera Francisca; Olive-Marques Alejandro; Alvarez del Buergo Maria; Marena-Rojas Luisa; Fernandez-Lopez Carlos; Navarro Francisco; Raya Enrique; Galindez-Agirregoikoa Eva; Arca Beatriz; Solans-Laque Roser; Conesa Arantxa; Hidalgo Cristina; Vazquez Carlos; Andres Roman-Ivorra Jose; Lluch Pau; Manrique-Arija Sara; Vela Paloma; De Miguel Eugenio; Torres-Martin Carmen; Carlos Nieto Juan; Ordas-Calvo Carmen; Salgado-Perez Eva; Luna-Gomez Cristina; Toyos-Saenz de Miera F. Javier; Fernandez-Llanio Nagore; Garcia Antonio; Larena Carmen; Palmou-Fontana Natalia; Calvo-Rio Vanesa; Prieto-Pena Diana; Gonzalez-Vela Carmen; Corrales Alfonso; Varela-Garcia Maria; Aurrecoechea Elena; Dos Santos Raquel; Garcia-Manzanares Angel; Ortego Norberto; Fernandez Sabela; Ortiz-Sanjuan Francisco; Corteguera Montserrat; Hernandez Jose L.; Gonzalez-Gay Miguel A.; Blanco Ricardo

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Tocilizumab in giant cell arteritis. Observational, open-label multicenter study of 134 patients in clinical practice

机译：在巨细胞动脉炎中进行康核。 134例临床实践中134名患者的观测性，开放式多中心研究

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Objective: Tocilizumab (TCZ) has shown efficacy in clinical trials on giant cell arteritis (GCA). Real-world data are scarce. Our objective was to assess efficacy and safety of TCZ in unselected patients with GCA in clinical practice

机译：目的：康斯之耳（TCZ）在巨型细胞动脉炎（GCA）上显示了临床试验的疗效。真实世界的数据很少。我们的目标是评估TCZ在未选择性患者在临床实践中的疗效和安全性

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来源
《Seminars in Arthritis and Rheumatism》 |2019年第1期|共10页
作者
Calderon-Goercke Monica; Loricera Javier; Aldasoro Vicente; Castaneda Santos; Villa Ignacio; Humbria Alicia; Moriano Clara; Romero-Yuste Susana; Narvaez Javier; Gomez-Arango Catalina; Perez-Pampin Eva; Melero Rafael; Becerra-Fernandez Elena; Revenga Marcelino; Alvarez-Rivas Noelia; Galisteo Caries; Sivera Francisca; Olive-Marques Alejandro; Alvarez del Buergo Maria; Marena-Rojas Luisa; Fernandez-Lopez Carlos; Navarro Francisco; Raya Enrique; Galindez-Agirregoikoa Eva; Arca Beatriz; Solans-Laque Roser; Conesa Arantxa; Hidalgo Cristina; Vazquez Carlos; Andres Roman-Ivorra Jose; Lluch Pau; Manrique-Arija Sara; Vela Paloma; De Miguel Eugenio; Torres-Martin Carmen; Carlos Nieto Juan; Ordas-Calvo Carmen; Salgado-Perez Eva; Luna-Gomez Cristina; Toyos-Saenz de Miera F. Javier; Fernandez-Llanio Nagore; Garcia Antonio; Larena Carmen; Palmou-Fontana Natalia; Calvo-Rio Vanesa; Prieto-Pena Diana; Gonzalez-Vela Carmen; Corrales Alfonso; Varela-Garcia Maria; Aurrecoechea Elena; Dos Santos Raquel; Garcia-Manzanares Angel; Ortego Norberto; Fernandez Sabela; Ortiz-Sanjuan Francisco; Corteguera Montserrat; Hernandez Jose L.; Gonzalez-Gay Miguel A.; Blanco Ricardo;
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作者单位

Univ Cantabria Hosp Univ Marques Valdecilla IDIVAL Dept Rheumatol Santander Spain;

Univ Cantabria Hosp Univ Marques Valdecilla IDIVAL Dept Rheumatol Santander Spain;

Complejo Hosp Navarra Dept Rheumatol Navarra Spain;

Hosp Univ La Princesa IIS Princesa Dept Rheumatol Madrid Spain;

Hosp Sierrallana Dept Rheumatol Torrelavega Spain;

Hosp Univ La Princesa IIS Princesa Dept Rheumatol Madrid Spain;

Complejo Asistencial Univ Leon Dept Rheumatol Leon Spain;

Complejo Hosp Univ Pontevedra Dept Rheumatol Pontevedra Spain;

Hosp Bellvitge Princeps Espanya Dept Rheumatol Barcelona Spain;

Hosp Alto Deba Dept Rheumatol Arrasate Mondragon Spain;

Complejo Hosp Univ Santiago Dept Rheumatol Santiago De Compostela Spain;

Complexo Hosp Univ Vigo Dept Rheumatol Vigo Spain;

Hosp Univ Torrevieja Dept Rheumatol Alicante Spain;

Hosp Ramon &

Cajal Dept Rheumatol Madrid Spain;

Hosp Univ Lucus Augusti Dept Rheumatol Lugo Spain;

Hosp Parc Taull Dept Rheumatol Barcelona Spain;

Hosp Univ Elda Dept Rheumatol Alicante Spain;

Hosp Trias &

Pujol Dept Rheumatol Badalona Spain;

Hosp Rio Carr Dept Rheumatol Palencia Spain;

Hosp Mancha Ctr Dept Rheumatol Alcazar De San Juan Spain;

Hosp Univ Juan Canalejo Dept Rheumatol La Coruna Spain;

Hosp Gen Univ Elche Dept Rheumatol Alicante Spain;

Hosp San Cecilio Dept Rheumatol &

Internal Med Granada Spain;

Hosp Basurto Dept Rheumatol Bilbao Spain;

Hosp Univ San Agustin Dept Rheumatol Aviles Spain;

Hosp Valle De Hebron Dept Internal Med Barcelona Spain;

Hosp Gen Univ Castellon Dept Rheumatol Castellon De La Plana Spain;

Complejo Asistencial Univ Salamanca Dept Rheumatol Salamanca Spain;

Hosp Miguel Servet Dept Rheumatol Zaragoza Spain;

Hosp Univ &

Politecn La Fe Dept Rheumatol Valencia Spain;

Hosp Mateu Orfila Dept Rheumatol Menorca Spain;

Hosp Reg Malaga Dept Rheumatol Malaga Spain;

Hosp Gen Univ Alicante Dept Rheumatol Alicante Spain;

Hosp La Paz Dept Rheumatol Madrid Spain;

Complejo Asistencial Avila Dept Rheumatol Avila Spain;

Hosp Gregorio Maranon Dept Rheumatol Madrid Spain;

Hosp Cabuenes Dept Rheumatol Gijon Spain;

Complejo Hosp Univ Ourense Dept Rheumatol Orense Spain;

Hosp Univ Nuestra Senora Candelaria Dept Rheumatol Tenerife Spain;

Hosp Univ Virgen Macarena Dept Rheumatol Seville Spain;

Hosp Arnau Vilanova Dept Rheumatol Lerida Spain;

Hosp Virgen Nieves Dept Rheumatol Granada Spain;

Hosp Ramon &

Cajal Dept Rheumatol Madrid Spain;

Univ Cantabria Hosp Univ Marques Valdecilla IDIVAL Dept Rheumatol Santander Spain;

Univ Cantabria Hosp Univ Marques Valdecilla IDIVAL Dept Rheumatol Santander Spain;

Univ Cantabria Hosp Univ Marques Valdecilla IDIVAL Dept Rheumatol Santander Spain;

Univ Cantabria Hosp Univ Marques Valdecilla IDIVAL Dept Rheumatol Santander Spain;

Univ Cantabria Hosp Univ Marques Valdecilla IDIVAL Dept Rheumatol Santander Spain;

Complejo Hosp Navarra Dept Rheumatol Navarra Spain;

Hosp Sierrallana Dept Rheumatol Torrelavega Spain;

Complejo Hosp Univ Santiago Dept Rheumatol Santiago De Compostela Spain;

Hosp Univ Torrevieja Dept Rheumatol Alicante Spain;

Hosp San Cecilio Dept Rheumatol &

Internal Med Granada Spain;

Hosp Univ San Agustin Dept Rheumatol Aviles Spain;

Hosp Univ &

Politecn La Fe Dept Rheumatol Valencia Spain;

Complejo Asistencial Avila Dept Rheumatol Avila Spain;

Univ Cantabria Hosp Univ Marques Valdecilla IDIVAL Dept Rheumatol Santander Spain;

Univ Cantabria Hosp Univ Marques Valdecilla IDIVAL Dept Rheumatol Santander Spain;

Univ Cantabria Hosp Univ Marques Valdecilla IDIVAL Dept Rheumatol Santander Spain;

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原文格式 PDF
正文语种 eng
中图分类免疫性疾病;
关键词
Tocilizumab; Giant cell arteritis; Biological therapy; Large-vessel vasculitis;

机译：对康氏菌布;巨细胞动脉炎;生物疗法;大血管血管炎;

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专利

1. Tocilizumab in giant cell arteritis. Observational, open-label multicenter study of 134 patients in clinical practice [J] . Calderon-Goercke Monica, Loricera Javier, Aldasoro Vicente, Seminars in Arthritis and Rheumatism . 2019,第1期

机译：在巨细胞动脉炎中进行康核。 134例临床实践中134名患者的观测性，开放式多中心研究
2. Tocilizumab in giant cell arteritis: Multicenter open-label study of 22 patients [J] . Loricera Javier, Blanco Ricardo, Hernandez Jose L., Seminars in Arthritis and Rheumatism . 2015,第6期

机译：在巨细胞动脉炎中的康康替毒液：22例患者的多中心开放标签研究
3. Serum osteopontin: a biomarker of disease activity and predictor of relapsing course in patients with giant cell arteritis. Potential clinical usefulness in tocilizumab-treated patients [J] . Nekane Terrades-García, Marc Corbera-Bellalta, Ester Planas-Rigol, RMD Open . 2017,第2期

机译：血清骨桥蛋白：巨细胞性动脉炎患者疾病活动的生物标志物和复发过程的预测因子。托珠单抗治疗的患者的潜在临床价值
4. An open-label, multicenter, randomized,comparative, safety, efficacy, cycle control,and quality of life study of CTR 25, Alesse ,and Ortho Tri-Cyclen [C] . Victoria Davis, Brian Hauck, Sheila Dunn, World Congress on Fertility and Sterility . 2004

机译：开放标签，多中心，随机，比较，安全，疗效，循环控制和CTR 25，Alesse和Ortho Tri-Cyclen的生命研究
5. Efficacy and safety of novel collagen conduits filled with collagen filaments to treat patients with peripheral nerve injury: A multicenter, controlled, open-label clinical trial [D] . Saeki Masaomi, 佐伯将臣 2019

机译：充满胶原细丝的新型胶原蛋白导管治疗周围神经损伤患者的疗效和安全性：一项多中心，对照，开放标签的临床试验
6. Original article: Serum osteopontin: a biomarker of disease activity and predictor of relapsing course in patients with giant cell arteritis. Potential clinical usefulness in tocilizumab-treated patients [O] . Sergio Prieto-González, Nekane Terrades-García, Marc Corbera-Bellalta, 2012

机译：原始文章：血清骨桥蛋白：巨细胞性动脉炎患者疾病活动的生物标志物和复发过程的预测因子。托珠单抗治疗的患者的潜在临床价值
7. OP0065 TOCILIZUMAB IN VISUAL INVOLVEMENT OF GIANT CELL ARTERITIS. MULTICENTER STUDY OF 312 PATIENTS OF CLINICAL PRACTICE [O] . L. Sanchez-Bilbao, J. Loricera, V. Aldasoro, 2021

机译：OP0065在巨型细胞动脉炎的视觉参与中染色体。 312例临床实践患者的多中心研究

Tocilizumab in giant cell arteritis. Observational, open-label multicenter study of 134 patients in clinical practice

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