Anxiolytic Activity of 11 H-2,3,4,5-Tetrahydro[1,3]Diazepino[1,2- a]Benzimidazole and 2-Mercaptobenzimizadole Derivatives

摘要

Abstract— This paper presents a study of the anxiolytic activity of compounds that belong to two classes of chemical groups: derivatives of 11 H -2,3,4,5-tetrahydro[1,3]diazepino[1,2- a ]benzimidazole (BIF) and derivatives of 2-mercaptobenzimidazole (AZH). The study has revealed that the studied compounds exhibit different degrees of tranquilizing action. The most potent anxiolytics were compounds BIF-66 and AZH-57. These compounds hold promise for an in-depth study of their neuropsychotropic profile.