The ARMS2 A69S Polymorphism Is Associated with Delayed Rod-Mediated Dark Adaptation in Eyes at Risk for Incident Age-Related Macular Degeneration

Mullins Robert F.; McGwin Gerald Jr.; Searcey Karen; Clark Mark E.; Kennedy Elizabeth L.; Curcio Christine A.; Stone Edwin M.; Owsley Cynthia

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The ARMS2 A69S Polymorphism Is Associated with Delayed Rod-Mediated Dark Adaptation in Eyes at Risk for Incident Age-Related Macular Degeneration

机译：ARMS2 A69S多态性与发生事故年龄相关性黄斑变性的风险的眼睛中的延迟杆介导的深色适应相关

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Purpose: To examine the association between sequence variants in genetic risk factors for age-related macular degeneration (AMD) and delayed rod-mediated dark adaptation (RMDA), the first functional biomarker for incident AMD, in older adults with normal macular health and early AMD.

机译：目的：检查年龄相关性黄斑（AMD）和延迟杆介导的肾脏危险因素的序列变体与延迟杆介导的暗适应（RMDA），在较常见的黄斑和早期患者中的第一个功能生物标志物。 amd。

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《Ophthalmology》 |2019年第4期|共10页
作者
Mullins Robert F.; McGwin Gerald Jr.; Searcey Karen; Clark Mark E.; Kennedy Elizabeth L.; Curcio Christine A.; Stone Edwin M.; Owsley Cynthia;
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作者单位

Univ Iowa Dept Ophthalmol &

Visual Sci Iowa City IA USA;

Univ Alabama Birmingham Dept Epidemiol Birmingham AL USA;

Univ Alabama Birmingham Dept Ophthalmol &

Visual Sci Birmingham AL USA;

Univ Alabama Birmingham Dept Ophthalmol &

Visual Sci Birmingham AL USA;

Univ Iowa Dept Ophthalmol &

Visual Sci Iowa City IA USA;

Univ Alabama Birmingham Dept Ophthalmol &

Visual Sci Birmingham AL USA;

Univ Iowa Dept Ophthalmol &

Visual Sci Iowa City IA USA;

Univ Alabama Birmingham Dept Ophthalmol &

Visual Sci Birmingham AL USA;

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正文语种 eng
中图分类眼科学;
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1. The ARMS2 A69S Polymorphism Is Associated with Delayed Rod-Mediated Dark Adaptation in Eyes at Risk for Incident Age-Related Macular Degeneration [J] . Mullins Robert F., McGwin Gerald Jr., Searcey Karen, Ophthalmology . 2019,第4期

机译：ARMS2 A69S多态性与发生事故年龄相关性黄斑变性的风险的眼睛中的延迟杆介导的深色适应相关
2. A69S and R38X ARMS2 and Y402H CFH gene polymorphisms as risk factors for neovascular age-related macular degeneration in Poland – a brief report [J] . S?awomir J. Teper, Anna Nowińska, Edward Wyl?ga?a Medical science monitor : . 2012,第9期

机译：A69S和R38X ARMS2和Y402H CFH基因多态性是波兰新血管性年龄相关性黄斑变性的危险因素–简要报告
3. Association of combined complement factor H Y402H and ARMS2/LOC387715 A69S polymorphisms with age-related macular degeneration: an updated meta-analysis [J] . Jabbarpoor Bonyadi Mohammad Hossein, Yaseri Mehdi, Soheilian Masoud Ophthalmic genetics . 2020,第4期

机译：组合补体系数H y402h和Arms2 / Loc387715 A69S与年龄相关性黄斑变性的多态性：更新的荟萃分析
4. Investigation of retinal microstructure in healthy eyes and dry age-related macular degeneration using a combined AO-OCT-SLO system [C] . Elaine M. Wells-Gray, Stacey S. Choi, Matthew Ohr, Ophthalmic technologies XXVII . 2017

机译：使用组合式AO-OCT-SLO系统研究健康眼睛的视网膜微结构和与干龄相关的黄斑变性
5. Gene-environment interaction in age-related macular degeneration: Exogenous estrogen, cigarette smoking, and VEGF pathway polymorphisms. [D] . Courtenay, Monique Dorcel. 2014

机译：年龄相关性黄斑变性中的基因-环境相互作用：外源性雌激素，吸烟和VEGF途径多态性。
6. Delayed Rod-Mediated Dark Adaptation is a Functional Biomarker for Incident Early Age-Related Macular Degeneration [O] . Cynthia Owsley, Gerald McGwin Jr, Mark E. Clark, -1

机译：延迟杆介导的暗适应是事件早期与年龄有关的黄斑变性的功能性生物标志物。
7. The ARMS2 A69S Polymorphism Is Associated with Delayed Rod-Mediated Dark Adaptation in Eyes at Risk for Incident Age-Related Macular Degeneration [O] . Robert F. Mullins, Gerald McGwin, Karen Searcey, 2019

机译：Therm2 A69s多态性与发生事故年龄相关性黄斑变性的风险的眼睛中的延迟杆介导的深色适应相关

The ARMS2 A69S Polymorphism Is Associated with Delayed Rod-Mediated Dark Adaptation in Eyes at Risk for Incident Age-Related Macular Degeneration

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