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The Use of Predictive Markers for the Development of a Model to Predict Weight Loss Following Vertical Sleeve Gastrectomy

机译:使用预测标记来开发模型以预测垂直套管胃切除术后的重量损失

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BackgroundAverage percent excess weight loss data is commonly discussed preoperatively to guide patient expectations following surgery. However, there is a wide range and variation in weight loss following vertical sleeve gastrectomy (SG). Unfortunately, most surgeons and even fewer patients have heard of using predictive models to help guide their decisions on procedure choice. We have developed a predictive model for SG to help patient choice prior to this major life-changing decision.ObjectivePredict weight loss results for SG patients at 1year using preoperative data.SettingPrivate practice.MethodsThree hundred and seventy-one SG patients met the criteria for our study. These patients underwent surgery between October 2008 and June 2016. Non-linear regressions were performed to interpolate individual patient weights at 1year. Multivariate analysis was used to find factors that affected weight loss. A model was constructed to predict weight loss performance.ResultsVariables that affect weight loss were found to be preoperative body mass index (BMI), age, hypertension, and diabetes. Diabetes and hypertension together were found to significantly affect weight loss.ConclusionPatient weight loss can be accurately predicted by simple preoperative factors. These findings should be used to help patients and surgeons decide if the SG is an appropriate surgery for each patient. Using this model, most patients can avoid failure by choosing an appropriate surgical approach for their personal circumstances.
机译:Backgroundaverage百分比百分比通常术后讨论了手术后引导患者期望。然而,在垂直套管胃切除术(SG)之后,体重减轻的宽范围和变化。不幸的是,大多数外科医生甚至更少的患者都听说过使用预测模型来帮助指导他们对程序选择的决定。我们已经开发了一个预测模型,以帮助在这个主要的生命变化的决策之前帮助患者选择。使用术前数据的SG患者的SG患者的重量损失结果.Settingprivate Deptring.Methodsthree百和七十一名SG患者达到了我们的标准学习。这些患者在2008年10月和2016年6月之间进行了手术。进行非线性回归,以在1年的1年内插入个体患者体重。多变量分析用于找到影响体重减轻的因素。构建模型以预测减肥性能。发现影响体重减轻的方法是术前体重指数(BMI),年龄,高血压和糖尿病。发现糖尿病和高血压在一起显着影响体重减轻。通过简单的术前因子可以准确地预测能力减肥。这些发现应该用于帮助患者和外科医生确定SG是否是每个患者的适当手术。使用此模型,大多数患者可以通过选择适当的外科手术方法来避免失败的个人情况。

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