Chiral Supercritical Fluid Chromatography of 1,2-Aminoalcohols (Review)

摘要

Preparative separation of enantiomers is one of the most common applications of supercritical fluid technologies in modern production practice. In this review, methods for the preparative separation of enantiomers of pharmaceutical substances in which a 1,2-aminoalcohol moiety is present are provided, using supercritical fluid chromatography. The types of chiral phases used in supercritical fluid chromatography are also considered in brief.