On-Site Test to Detect Syphilis in Pregnancy: A Systematic Review of Test Accuracy Studies

摘要

Syphilis, an infection of the Treponema pallidum bacterium, can easily go undetected. This sexually transmitted infection can affect pregnant women and lead to adverse outcomes through vertical infection including congenital anomalies and neonatal death. The World Health Organization supports screening all pregnant women, and on-site tests are an important tool for effective screening. This review aims to assess immunochromatographic point-of-care treponemal tests for accuracy and compare these tests with the rapid plasma reagin (RPR) card.