Synthesis of New Fused Pirano[4,3-b]pyridine Derivatives

摘要

A method was developed for the synthesis of pyrano[4,3-b]thieno[3,2-e]pyridine derivatives based on the reaction of 3-amino-7-ethyl-7-methyl-7,8-dihydro-5H-pyrano[4,3-b]thieno[3,2-e]pyridine-2-carboxylic acid ethyl ester with chloroacetic acid chloride, triethyl orthoformate, hydrazine hydrate, and also phenyl chloroformate. The synthesis of various new representatives of pyrano[2 '',3 '':5 ',6 ']pyrido[3 ',2 ':4,5]thieno[3,2-dl-pyrimidine series was carried out.