Synthesis, Structure, and Antimicrobial Activity of Methyl (4-Alkanoyl-3-hydroxy-1,5-diaryl-1H-pyrrol-2-yl) acetates

摘要

Reactions of methyl 3,4,6-trioxoalkanoates (3,4-dihydroxy-6-oxo-2,4-alkadienoates) with a mixture of arylamines and aromatic aldehydes or with the corresponding arylidenearylamines lead to the formation of methyl (4- alkanoyl-3-hydroxy-1,5-diaryl-1H-pyrrol-2-yl)acetates. Structure of the synthesized compounds is discussed basing on IR, H-1 NMR spectroscopy, mass spectrometry, and X-ray diffraction data.