Synthesis and Antibacterial Activity of Novel 4-{4-(Methylamino)thieno[3,2-d]pyrimidin-2-yl}-benzohydrazide Derivatives

摘要

A series of novel 4-{4-(methylamino)thieno[3,2-d]pyrimidin-2-yl}benzohydrazide derivatives were synthesized and evaluated for their antibacterial activity. Most of the compounds demonstrated high activity towards Escherichia coli, Pseudomonas, Staphylococcus aureus, and Bacillus. Structures of all synthesized compounds were confirmed by spectral analysis.