Synthesis and characterization of some novel 1,3-diaryl pyrazole bearing 2-oxopyridine-3,5-dicarbonitrile derivatives

摘要

A series of new 1-{[1-(3-chlorophenyl)-3-(4-methoxyphenyl)-1H-pyrazol-4-yl]methyleneamino}-6-amino-1,2-dihydro-4-(substitutedphenyl)-2-oxopyridine-3,5-di carbonitrile derivatives (4a-4i) were synthesized and characterized via cyclization of the key intermediate (E)-N'-([1-(3-chlorophenyl)-3-(4-methoxyphenyl)-1H-pyrazol-4-yl]methylene}-2-cyanoaceto hydrazide with different 2-arylidenemalononitrile.