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CT-based MCNPX dose calculations for gynecology brachytherapy employing a Henschke applicator

机译:基于CT的MCNPX剂量计算,用于携带HENSCHKE涂药器的妇科近距离放射治疗

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The purpose of this study is to investigate the dose perturbation caused by the metal ovoid structures of a Henschke applicator using Monte Carlo simulation in a realistic phantom. The Henschke applicator has been widely used for gynecologic patients treated by brachytherapy in Taiwan. However, the commercial brachytherapy planning system (BPS) did not properly evaluate the dose perturbation caused by its metal ovoid structures. In this study, Monte Carlo N-Particle Transport Code eXtended (MCNPX) was used to evaluate the brachytherapy dose distribution of a Henschke applicator embedded in a Plastic water phantom and a heterogeneous patient computed tomography (CT) phantom. The dose comparison between the MC simulations and film measurements for a Plastic water phantom with Henschke applicator were in good agreement. However, MC dose with the Henschke applicator showed significant deviation (-80.6% +/- 7.5%) from those without Henschke applicator. Furthermore, the dose discrepancy in the heterogeneous patient CT phantom and Plastic water phantom CT geometries with Henschke applicator showed 0 to -26.7% dose discrepancy (-8.9% +/- 13.8%). This study demonstrates that the metal ovoid structures of Henschke applicator cannot be disregard in brachytherapy dose calculation.
机译:本研究的目的是研究HENSCHKE涂敷器的金属卵形结构引起的剂量扰动,在逼真的幽灵中使用Monte Carlo仿真。亨氏涂药器已广泛用于台湾近距离放射治疗治疗的妇科患者。然而,商业近距离放射治疗系统(BPS)未正确评估其金属卵形结构引起的剂量扰动。在本研究中,蒙特卡罗N-粒子传输代码延长(MCNPX)来评估嵌入塑料水体模型的亨氏涂敷器的近距离放射治疗剂量分布和异质患者计算断层扫描(CT)幻影。 MC模拟与HENSCHKE涂敷器的塑料水模拟和薄膜测量之间的剂量比较良好。然而,MC剂量与HENSCHKE涂敷器的偏差显示出的偏差(-80.6%+/- 7.5%),没有亨克克克克克克施加器。此外,异质患者CT幻影和塑料水幻影CT几何形剂量差异与亨氏涂敷器显示0至-26.7%的剂量差异(-8.9%+/- 13.8%)。本研究表明,亨氏涂敷器的金属卵形结构不能忽略近距离放射治疗剂量计算。

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