Inhibitory Effect of Hydroxysafflor Yellow B on the Proliferation of Human Breast Cancer MCF-7 Cells

Qu Chuanjun; Zhu Weiwei; Dong Kaijie; Pan Zhaohai; Chen Ying; Chen Xiaoyu; Liu Xiaona; Xu Wenjuan; Lin Haiyan; Zheng Qiusheng; Li Defang

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Inhibitory Effect of Hydroxysafflor Yellow B on the Proliferation of Human Breast Cancer MCF-7 Cells

机译：羟基烷烃黄B对人乳腺癌MCF-7细胞增殖的抑制作用

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Background: A recent patent has been issued for hydroxysafflor yellow A (HSYA) as a drug to prevent blood circulation disorders. Hydroxysafflor yellow B (HSYB), an isomer of HSYA with anti-oxidative effects, has been isolated from the florets of Carthamus tinctorius. The effects of HSYB on the proliferation of cancer cells and its mechanism of action have not been investigated.

机译：背景：最近的专利是为羟基烷烃黄色A（HSYA）作为一种药物，以防止血液循环障碍。 Hydroxafflor黄B（HSYB），HSYA的异构体具有抗氧化作用，已从Carthamus Tinctorius的小花中分离出来。 HSSYB对癌细胞增殖及其作用机制的影响尚未研究。

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来源
《Recent patents on anti-cancer drug discovery》 |2019年第2期|共11页
作者
Qu Chuanjun; Zhu Weiwei; Dong Kaijie; Pan Zhaohai; Chen Ying; Chen Xiaoyu; Liu Xiaona; Xu Wenjuan; Lin Haiyan; Zheng Qiusheng; Li Defang;
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作者单位

Binzhou Med Univ Sch Integrated Tradit Chinese &

Western Med Yantai Key Lab Pharmacol Tradit;

Qingdao Univ Dept Pharm Yantai Yuhuangding Hosp Yantai 264000 Peoples R China;

Binzhou Med Univ Yantai Affiliated Hosp Yantai 264003 Peoples R China;

Binzhou Med Univ Sch Integrated Tradit Chinese &

Western Med Yantai Key Lab Pharmacol Tradit;

Binzhou Med Univ Sch Integrated Tradit Chinese &

Western Med Yantai Key Lab Pharmacol Tradit;

Binzhou Med Univ Sch Integrated Tradit Chinese &

Western Med Yantai Key Lab Pharmacol Tradit;

Binzhou Med Univ Sch Integrated Tradit Chinese &

Western Med Yantai Key Lab Pharmacol Tradit;

Binzhou Med Univ Sch Integrated Tradit Chinese &

Western Med Yantai Key Lab Pharmacol Tradit;

Binzhou Med Univ Sch Integrated Tradit Chinese &

Western Med Yantai Key Lab Pharmacol Tradit;

Binzhou Med Univ Sch Integrated Tradit Chinese &

Western Med Yantai Key Lab Pharmacol Tradit;

Binzhou Med Univ Sch Integrated Tradit Chinese &

Western Med Yantai Key Lab Pharmacol Tradit;

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原文格式 PDF
正文语种 eng
中图分类药学;
关键词
Breast cancer; cell apoptosis; cell cycle arrest; cell proliferation; hydroxysafflor yellow B; MCF-7 cells;

机译：乳腺癌;细胞凋亡;细胞周期骤停;细胞增殖;羟基烷烷烃黄b;MCF-7细胞;

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专利

1. Inhibitory Effect of Hydroxysafflor Yellow B on the Proliferation of Human Breast Cancer MCF-7 Cells [J] . Qu Chuanjun, Zhu Weiwei, Dong Kaijie, Recent patents on anti-cancer drug discovery . 2019,第2期

机译：羟基烷烃黄B对人乳腺癌MCF-7细胞增殖的抑制作用
2. Combinations of parabens at concentrations measured in human breast tissue can increase proliferation of MCF-7 human breast cancer cells [J] . Journal of applied toxicology . 2013,第5a6期

机译：在人的乳腺组织中检测到浓度的对羟基苯甲酸酯类组合可增加MCF-7人乳腺癌细胞的增殖
3. Inhibitory effects of hydroxysafflor yellow A on PDGF-BB-induced proliferation and migration of vascular smooth muscle cells via mediating Akt signaling [J] . SongY., LongL., ZhangN., Molecular medicine reports . 2014,第3期

机译：羟基红花黄素A通过介导Akt信号转导对PDGF-BB诱导的血管平滑肌细胞增殖和迁移的抑制作用
4. Effects of the Gold Nanoparticles (AuNPs) on the Proliferation and Morphological Characteristics of Human Breast Cancer Cells (MCF-7) in Culture [C] . Nur Shafawati Rosli, Azhar Abdul Rahman, Azlan Abdul Aziz, Regional Conference of Solid State Science and Technology . 2017

机译：金纳米粒子（AUNP）对培养中人乳腺癌细胞（MCF-7）的增殖和形态特征的影响
5. The effects of the extract of Rubaiyat, an Oklahoma grape variety, and resveratrol on cellular proliferation and apoptosis of MCF-7 human breast cancer cells. [D] . Luebcke, Emily D. 2009

机译：俄克拉荷马州葡萄品种Rubaiyat的提取物和白藜芦醇对MCF-7人乳腺癌细胞的细胞增殖和凋亡的影响。
6. The Inhibitory Effect of Cordycepin on the Proliferation of MCF-7 Breast Cancer Cells, and Its Mechanism: An Investigation Using Network Pharmacology-Based Analysis [O] . Dahae Lee, Won-Yung Lee, Kiwon Jung, 1801

机译：虫草素对MCF-7乳腺癌细胞增殖的抑制作用及其机制：基于网络药理学的研究
7. A shift from normal to high glucose levels stimulates cell proliferation in drug sensitive MCF-7 human breast cancer cells but not in multidrug resistant MCF-7/ADR cells which overproduce PKC-?II [O] . Mayumi Yamamoto, Niketa A. Patel, Jennifer Taggart, 1999

机译：从正常到高葡萄糖水平的偏移刺激药物敏感MCF-7人乳腺癌细胞中的细胞增殖，但不在多药抗性MCF-7 / ADR细胞中，其过度提出PKC-？II

Inhibitory Effect of Hydroxysafflor Yellow B on the Proliferation of Human Breast Cancer MCF-7 Cells

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