Anti-Cancer Effect of alpha-Solanine by Down-Regulating S100P Expression in Colorectal Cancer Cells

Ni Xiaofen; Chen Jiajun; Lu Fengying; Yuan Zhengzhong; Xu Xiaofeng; Hu Zhen; Jiang Lei

首页> 外文期刊>Recent patents on anti-cancer drug discovery >Anti-Cancer Effect of alpha-Solanine by Down-Regulating S100P Expression in Colorectal Cancer Cells

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Anti-Cancer Effect of alpha-Solanine by Down-Regulating S100P Expression in Colorectal Cancer Cells

机译：通过在结直肠癌细胞中降低S100P表达的α-溶解抗癌作用

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摘要

Background: alpha-Solanine, the most important and active component of Solanum nigrum, was found to have anti-cancer activity on multiple cancer cells. However, its effects on colorectal cancer (CRC) and associated molecular mechanisms remain to be further elucidated.

机译：背景：发现α-溶含量，最重要和活性组分Solanum nigrum，在多种癌细胞上具有抗癌活性。然而，它对结直肠癌（CRC）和相关分子机制的影响仍然待进一步阐明。

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来源
《Recent patents on anti-cancer drug discovery》 |2018年第2期|共8页
作者
Ni Xiaofen; Chen Jiajun; Lu Fengying; Yuan Zhengzhong; Xu Xiaofeng; Hu Zhen; Jiang Lei;
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作者单位

Wenzhou Med Univ Dept Tradit Chinese Med Affiliated Hosp 1 Wenzhou 325000 Peoples R China;

Wenzhou Med Univ Dept Tradit Chinese Med Affiliated Hosp 2 Wenzhou 325000 Peoples R China;

Wenzhou Med Univ Cent Lab Affiliated Hosp 1 Wenzhou 325000 Zhejiang Peoples R China;

Wenzhou Med Univ Dept Tradit Chinese Med Affiliated Hosp 1 Wenzhou 325000 Peoples R China;

Wenzhou Med Univ Dept Tradit Chinese Med Affiliated Hosp 1 Wenzhou 325000 Peoples R China;

Wenzhou Med Univ Dept Tradit Chinese Med Affiliated Hosp 2 Wenzhou 325000 Peoples R China;

Wenzhou Med Univ Cent Lab Affiliated Hosp 1 Wenzhou 325000 Zhejiang Peoples R China;

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原文格式 PDF
正文语种 eng
中图分类药学;
关键词
Anti-tumor effect; apoptosis; cell-cycle arrest; colorectal cancer; invasion; migration; S100P; alpha-solanine;

机译：抗肿瘤效应;细胞凋亡;细胞周期骤停;结直肠癌;入侵;迁移;S100P;α-甲酸盐;

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1. Anti-Cancer Effect of alpha-Solanine by Down-Regulating S100P Expression in Colorectal Cancer Cells [J] . Ni Xiaofen, Chen Jiajun, Lu Fengying, Recent patents on anti-cancer drug discovery . 2018,第2期

机译：通过在结直肠癌细胞中降低S100P表达的α-溶解抗癌作用
2. Anti-inflammatory actions of plant-derived multiple monoclonal antibody CO17-1AxBR55 related with anti-cancer effects in AOM/DSS-induced colorectal cancer mouse via down-regulating of ERK1/2 [J] . Kwak Dong Hoon, Heo Sung Yun, Kim Chang-Hyun, Animal Cells and Systems . 2016,第4期

机译：植物源性多重单克隆抗体CO17-1AxBR55的抗炎作用与下调ERK1 / 2对AOM / DSS诱导的结直肠癌小鼠的抗癌作用有关
3. Anti-inflammatory actions of plant-derived multiple monoclonal antibody CO17-1A?×?BR55 related with anti-cancer effects in AOM/DSS-induced colorectal cancer mouse via down-regulating of ERK1/2 [J] . Dong Hoon Kwak, Sung Yun Heo, Chang-Hyun Kim, Animal Cells and Systems . 2016,第4期

机译：植物源性多重单克隆抗体CO17-1Aα×ΔBR55的抗炎作用与下调ERK1 / 2对AOM / DSS诱导的结直肠癌小鼠的抗癌作用有关
4. QSAR Study of The Anti-cancer Activity of 38 Compounds in Different Cancer Cell Lines Based on Gene Expression Programming [C] . Xiurui Han, Xianchao Li, Hongzong Si International Forum on Materials Analysis and Testing Technology(IFMATT) . 2014

机译：基于基因表达规划的不同癌细胞系中38种化合物抗癌活性的QSAR研究
5. Investigating the multi-targeted anti-cancer and chemopreventive potential of GSE in pre-clinical models of colorectal cancer. [D] . Derry, Molly M. 2013

机译：在大肠癌的临床前模型中研究GSE的多目标抗癌和化学预防潜力。
6. Anti-cancer activity of Ginger (Zingiber officinale) leaf through the expression of activating transcription factor 3 in human colorectal cancer cells [O] . Gwang Hun Park, Jae Ho Park, Hun Min Song, 2014

机译：通过激活转录因子3在大肠癌细胞中的表达姜叶的抗癌活性
7. Anti-cancer activity of Ginger (Zingiber officinale) leaf through the expression of activating transcription factor 3 in human colorectal cancer cells [O] . Gwang Hun Park, Jae Ho Park, Hun Min Song, 2014

机译：通过激活转录因子3在大肠癌细胞中的表达，姜叶的抗癌活性

Anti-Cancer Effect of alpha-Solanine by Down-Regulating S100P Expression in Colorectal Cancer Cells

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