Anti-Oxidants as Chemopreventive Agents in Prostate Cancer: A Gap Between Preclinical and Clinical Studies

Mohsenzadegan Monireh; Seif Farhad; Farajollahi Mohammad M.; Khoshmirsafa Majid

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Anti-Oxidants as Chemopreventive Agents in Prostate Cancer: A Gap Between Preclinical and Clinical Studies

机译：抗氧化剂作为前列腺癌中化学预防剂：临床前与临床研究之间的差距

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Background: Tumor cells may be expressed as a result of oxidative stress. The extent of oxidative stress correlates with the aggressive and metastatic potency of cancer.

机译：背景：肿瘤细胞可以作为氧化应激表达。氧化应激程度与癌症的侵袭性和转移性效力相关。

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来源
《Recent patents on anti-cancer drug discovery》 |2018年第2期|共16页
作者
Mohsenzadegan Monireh; Seif Farhad; Farajollahi Mohammad M.; Khoshmirsafa Majid;
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作者单位

Iran Univ Med Sci Fac Allied Med Sci Dept Med Lab Sci Tehran Iran;

Iran Univ Med Sci Sch Med Dept Immunol Tehran Iran;

Iran Univ Med Sci Fac Allied Med Sci Dept Med Biotechnol Tehran Iran;

Iran Univ Med Sci Sch Med Dept Immunol Tehran Iran;

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原文格式 PDF
正文语种 eng
中图分类药学;
关键词
Antioxidants; chemopreventive agents; preclinical study; prostate cancer; reactive oxygen species; recent patents; clinical study;

机译：抗氧化剂;化学预防剂;临床前研究;前列腺癌;反应性氧物种;最近的专利;临床研究;

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1. Anti-Oxidants as Chemopreventive Agents in Prostate Cancer: A Gap Between Preclinical and Clinical Studies [J] . Mohsenzadegan Monireh, Seif Farhad, Farajollahi Mohammad M., Recent patents on anti-cancer drug discovery . 2018,第2期

机译：抗氧化剂作为前列腺癌中化学预防剂：临床前与临床研究之间的差距
2. Clinical trials of natural products as chemopreventive agents for prostate cancer [J] . Debra L Bemis, Aaron E Katz, Ralph Buttyan Expert opinion on investigational drugs . 2006,第10期

机译：天然产物作为前列腺癌化学预防剂的临床试验
3. Anthocyans as tertiary chemopreventive agents in bladder cancer: anti-oxidant mechanisms and interaction with mitomycin C. [J] . Jennifer A Higgins, Murizal Zainol, Karen Brown, Mutagenesis . 2014,第4期

机译：花青素作为膀胱癌的三级化学预防剂：抗氧化机制以及与丝裂霉素C的相互作用。
4. Clinical Models for Testing Chemopreventative Agents in Prostate Cancer and Overview of SELECT: The Selenium and Vitamin E Cancer Prevention Trial [C] . Eric A. Klein International Society of Cancer Chemoprevention . 2003

机译：用于测试前列腺癌中化学预防剂的临床模型及选择：硒和维生素E癌预防试验
5. Assessment of Black Raspberries for Prostate Cancer: Product Development for Clinical Intervention and Preclinical Study for Mechanism Investigation. [D] . Gu, Junnan. 2015

机译：黑莓治疗前列腺癌的评估：用于临床干预的产品开发和用于机制研究的临床前研究。
6. Prostate cancer prevention: review of target populations pathological biomarkers and chemopreventive agents. [O] . R Montironi, R Mazzucchelli, J R Marshall, 1999

机译：前列腺癌预防：审查目标人群病理生物标志物和化学预防剂。
7. The Effect of Cancer Chemopreventive Agents on DNA Adduct Formation by the Dietary Prostate Carcinogen PhIP [O] . Principal Investigator, Kenneth W. Turteltaub, Ph. D, 2016

机译：癌症化学预防剂对前列腺癌致癌物质形成DNa加合物的影响
8. Preclinical and Clinical Evaluation of Novel Agents for Noninvasive Imaging of Prostate Cancer [R] . Counsell, R. E. , Gross, M. D. , Wahl, R. L. 2002

机译：新型前列腺癌无创成像药物的临床前和临床评价

Anti-Oxidants as Chemopreventive Agents in Prostate Cancer: A Gap Between Preclinical and Clinical Studies

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