Simultaneous detection of hepatocellular carcinoma and vessel thrombus by using SPIOenhanced B-TFE with the T_2 preparation pulse technique

摘要

The purpose of this study was to compare between superparamagnetic iron oxide (SPIO)-enhanced three-dimensional balanced turbo field-echo (B-TFE) sequence with T_2 preparation pulse (T_2 prep) and T_2*-weighted imaging (T_2*WI) for the simultaneous detection of hepatocellular carcinoma (HCC) and vessel thrombus. For 1.5-T magnetic resonance imaging, SPIO was administered to 23 patients with a portal or venous tumor thrombus, and B-TFE with T_2 prep and T_2*WI were acquired. Regions of interest in the B-TFE and T_2*WI were selected for the tumor, liver, tumor thrombus, and vessels. The contrasts of the HCC in the liver and the tumor thrombus in the vessels were determined from clinical image. Contrast was calculated using the mean value of the signal intensity on the HCC to the liver and tumor thrombus to vessels.