Design, Synthesis and Evaluation of Thiourea Derivatives as Antimicrobial and Antiviral Agents

Ravichandran Veerasamy; Shalini Sivadasan; Kumar Krishnan Suresh; Rajak Harish; Agrawal Ram Kishore

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Design, Synthesis and Evaluation of Thiourea Derivatives as Antimicrobial and Antiviral Agents

机译：硫脲衍生物作为抗微生物和抗病毒剂的设计，合成和评价

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Background: The development of drug-resistant by bacteria appears rapidly and thus making the effectiveness of antibiotics severely limited.

机译：背景：细菌的耐药性迅速发展，从而使抗生素的有效性受到严重限制。

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来源
《Letters in drug design & discovery》 |2019年第6期|共7页
作者
Ravichandran Veerasamy; Shalini Sivadasan; Kumar Krishnan Suresh; Rajak Harish; Agrawal Ram Kishore;
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作者单位

AIMST Univ Dept Pharm Semeling 08100 Kedah Malaysia;

KMCH Coll Pharm Kovai Estate Kalapatti Rd Coimbatore Tamil Nadu India;

KMCH Coll Pharm Med Chem Res Lab Coimbatore Tamil Nadu India;

Guru Ghasidas Univ SLT Inst Pharmaceut Sci Med Chem Res Lab Bilaspur 495009 India;

Dr Hari Singh Gour Vishwavidyalaya Dept Pharmaceut Sci Sagar 470003 MP India;

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原文格式 PDF
正文语种 eng
中图分类生药学（天然药物学）;
关键词
Thioureas; antibacterial; antifungal; antiviral; anti-HIV; nucleosides;

机译：硫脲;抗菌;抗真菌;抗病毒;抗HIV;核苷;

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专利

1. Design, Synthesis and Evaluation of Thiourea Derivatives as Antimicrobial and Antiviral Agents [J] . Ravichandran Veerasamy, Shalini Sivadasan, Kumar Krishnan Suresh, Letters in drug design & discovery . 2019,第6期

机译：硫脲衍生物作为抗微生物和抗病毒剂的设计，合成和评价
2. Synthesis, biological evaluation and in silico study of bis-thiourea derivatives as anticancer, antimalarial and antimicrobial agents [J] . Ratchanok Pingaew, Nujarin Sinthupoom, Prasit Mandi, Medicinal chemistry research: an international journal for rapid communications on design and mechanisms of action of biologically active agents . 2017,第12期

机译：合成，生物学评价和双 - 硫脲衍生物的基石研究作为抗癌，抗疟和抗微生物剂
3. Synthesis and biological evaluation of some novel urea and thiourea derivatives of isoxazolo[4,5-d]pyridazine and structurally related thiazolo[4,5-d]pyridazine as antimicrobial agents [J] . FaidallahH.M., RostomS.A.F., BasaifS.A., Archives of pharmacal research . 2013,第11期

机译：异恶唑并[4,5-d]哒嗪和结构相关的噻唑并[4,5-d]哒嗪作为抗菌剂的一些新型脲和硫脲衍生物的合成及生物学评价
4. Synthesis and toxicological activity of 5-nitroindazole sulfonamides derivatives as potential antimicrobial agents. Optimization of the synthesis [C] . Corina Cheptea, Andreea-Celia Benchea, Marius Găină, 2017 E-Health and Bioengineering Conference . 2017

机译：5-硝基吲唑磺酰胺衍生物作为潜在抗菌剂的合成及其毒理活性。优化合成
5. Design, synthesis, and evaluation of small molecules in the discovery of novel antimicrobial agents [D] . Grimes, Kimberly D. 2008

机译：在发现新型抗微生物剂中设计，合成和评估小分子
6. Design synthesis and biological evaluation of novel substituted thiourea derivatives as potential anticancer agents for NSCLC by blocking K-Ras protein-effectors interactions [O] . Yuan Zhang, Xin Meng, Haikang Tang, 2020

机译：通过阻断K-Ras蛋白-效应子的相互作用设计合成和生物评估新型取代的硫脲衍生物作为NSCLC的潜在抗癌药
7. Synthesis, Biological Properties and Comparative Molecular Docking Evaluation Studies of 1,3 and 1,4 Bis-Thiourea Derivatives as Potential Antimicrobial Resistant Agents [O] . Wan Sharifatun Handayani Wan Zullkiplee, Ferlicia Rasin, Ainaa Nadiah Abd Halim, 2021

机译：1,3和1,4双硫脲衍生物作为潜在抗微生物抗性剂的合成，生物学性能和对比分子对比评价研究

Design, Synthesis and Evaluation of Thiourea Derivatives as Antimicrobial and Antiviral Agents

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