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首页> 外文期刊>NeuroRehabilitation >Treadmill exercise training could attenuate the upregulation of Interleukin-1 beta and tumor necrosis factor alpha in the skeletal muscle of mouse model of chronic/progressive Parkinson disease
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Treadmill exercise training could attenuate the upregulation of Interleukin-1 beta and tumor necrosis factor alpha in the skeletal muscle of mouse model of chronic/progressive Parkinson disease

机译:跑步机运动训练可以衰减白细胞介素-1β和肿瘤坏死因子α在慢性/普通帕金森病小鼠模型中的骨骼肌中的上调

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摘要

BACKGROUND: Induction of Parkinson disease (PD) causes interleukin-1 beta (IL-1 beta) and tumor necrosis factor-alpha (TNF-alpha) upregulation in gastrocnemius skeletal muscles. Endurance exercise suppresses iNOS and HSP90 overexpression in PD skeletal muscle. The purpose of this study is to test the impact of treadmill exercise training on PD-associated IL-1 beta and TNF-alpha upregulation in the gastrocnemius muscle.
机译:背景:帕金森病(Pd)诱导导致白细胞介素-1β(IL-1β)和肿瘤坏死因子-α(TNF-α)上调在胃肠杆菌骨骼肌中。 耐力锻炼在PD骨骼肌中抑制INOS和HSP90过表达。 本研究的目的是测试跑步机运动训练对PD相关的IL-1β和TNF-α的影响,在腓肠肌肌肉中的肌肉。

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