Tandem synthesis of benzo[d]naphtho[2,3-g][1,3]oxazocine-8,13(6H,14H)-dione derivatives

摘要

An efficient and facile method for the synthesis of novel naphthooxazocines from 2-hydroxy-1,4-naphthoquinone and quinolinium salts at room temperature is described. The reaction proceeds through C-alkylation and intramolecular O-alkylation, affording the desired products in good yields.