Role of diffusion weighted imaging for differentiating cerebral pilocytic astrocytoma and ganglioglioma BRAF V600E-mutant from wild type

Ramaglia Antonia; Tortora Domenico; Mankad Kshitij; Lequin Maarten; Severino Mariasavina; DArco Felice; Lobel Ulrike; Benenati Massimo; de Leng Wendy W. J.; De Marco Patrizia; Milanaccio Claudia; Rossi Andrea; Morana Giovanni

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Role of diffusion weighted imaging for differentiating cerebral pilocytic astrocytoma and ganglioglioma BRAF V600E-mutant from wild type

机译：扩散加权成像的作用，用于区分脑硫纤维星形细胞瘤和甘氨酸血清瘤BRAF V600E-突变体的野生型

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Purpose BRAF V600E mutation is a distinctive genomic alteration of pediatric low-grade gliomas with prognostic and therapeutic implications. The aim of this retrospective multicenter study was to analyze imaging features of BRAF V600E-mutant and wild-type cerebral pilocytic astrocytomas (PAs) and gangliogliomas (GGs), focusing on the role of diffusion weighted imaging (DWI).

机译：目的BRAF V600E突变是具有预后和治疗意义的小儿低级胶质瘤的独特基因组改变。该回顾性多中心研究的目的是分析BRAF V600E-突变体和野生型脑硫氰胞菌星形细胞瘤（PAS）和Gangliogliomas（GGS）的成像特征，重点是扩散加权成像（DWI）的作用。

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来源
《Neuroradiology》 |2020年第1期|共10页
作者
Ramaglia Antonia; Tortora Domenico; Mankad Kshitij; Lequin Maarten; Severino Mariasavina; DArco Felice; Lobel Ulrike; Benenati Massimo; de Leng Wendy W. J.; De Marco Patrizia; Milanaccio Claudia; Rossi Andrea; Morana Giovanni;
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作者单位

Fdn Policlin Univ A Gemelli IRCCS UOC Radiodiagnost &

Neuroradiol Dipartimento Diagnost Immagini;

IRCCS Ist Giannina Gaslini Neuroradiol Unit Via G Gaslini 5 I-16147 Genoa Italy;

Great Ormond St Hosp Children NHS Fdn Trust Dept Radiol London England;

Univ Med Ctr Dept Radiol Utrecht Netherlands;

IRCCS Ist Giannina Gaslini Neuroradiol Unit Via G Gaslini 5 I-16147 Genoa Italy;

Great Ormond St Hosp Children NHS Fdn Trust Dept Radiol London England;

Great Ormond St Hosp Children NHS Fdn Trust Dept Radiol London England;

Fdn Policlin Univ A Gemelli IRCCS UOC Radiodiagnost &

Neuroradiol Dipartimento Diagnost Immagini;

Univ Med Ctr Dept Pathol Utrecht Netherlands;

IRCCS Ist Giannina Gaslini Lab Neurogenet &

Neurosci Genoa Italy;

IRCCS Ist Giannina Gaslini Neurooncol Unit Genoa Italy;

IRCCS Ist Giannina Gaslini Neuroradiol Unit Via G Gaslini 5 I-16147 Genoa Italy;

IRCCS Ist Giannina Gaslini Neuroradiol Unit Via G Gaslini 5 I-16147 Genoa Italy;

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原文格式 PDF
正文语种 eng
中图分类放射医学;
关键词
Pilocytic astrocytoma; Ganglioglioma; Pediatric; BRAF V600E; Diffusion weighted imaging;

机译：pilocytic星形细胞瘤;Ganglioglioma;小儿;BRAF V600E;扩散加权成像;

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专利

1. Role of diffusion weighted imaging for differentiating cerebral pilocytic astrocytoma and ganglioglioma BRAF V600E-mutant from wild type [J] . Ramaglia Antonia, Tortora Domenico, Mankad Kshitij, Neuroradiology . 2020,第1期

机译：扩散加权成像的作用，用于区分脑硫纤维星形细胞瘤和甘氨酸血清瘤BRAF V600E-突变体的野生型
2. Diagnostic accuracy of diffusion weighted imaging for differentiation of supratentorial pilocytic astrocytoma and pleomorphic xanthoastrocytoma [J] . She Dejun, Liu Jianyi, Zeng Z., Neuroradiology . 2018,第7期

机译：扩散加权成像的诊断准确性，以分化超前硫纤维星形细胞瘤和最新的Xanthoastrocytoma
3. Usefulness of perfusion- and diffusion-weighted imaging to differentiate between pilocytic astrocytomas and high-grade gliomas: a multicenter study in Japan [J] . Kazufumi Kikuchi, Akio Hiwatashi, Osamu Togao, Neuroradiology . 2018,第4期

机译：灌注和扩散加权成像的有用性，以区分紫红色星形细胞瘤和高级胶质瘤：日本的多中心研究
4. Quantitative diffusion ??? Weighted imaging apparent diffusion coefficient values and perfusion ??? Weighted imaging relative cerebral blood volume in characterization of mixed gliomas (Grading II/III) [C] . Teodora-Anca Albu, Stanca-Mihaela Ple IEEE International Conference on E-Health and Bioengineering . 2015

机译：定量扩散加权成像表观扩散系数值和灌注混合脑胶质瘤表征中的加权成像相对脑血容量（II / III级）
5. Differentiating benign and malignant inflammatory breast lesions: Value of T2 weighted and diffusion weighted MR images [D] . Kanao, Shotaro 2019

机译：区分乳腺良性和恶性炎症病变：T2加权和弥散加权MR图像的价值
6. Diagnostic accuracy of diffusion weighted imaging for differentiation of supratentorial pilocytic astrocytoma and pleomorphic xanthoastrocytoma [O] . Dejun She, Jianyi Liu, Z. Zeng, -1

机译：弥散加权成像对上皮细胞性星形细胞瘤和多形性黄体星形细胞瘤的诊断准确性
7. Detection of BRAF V600E Mutation in Ganglioglioma and Pilocytic Astrocytoma by Immunohistochemistry and Real-Time PCR-Based Idylla Test [O] . Justyna Durślewicz, Anna Klimaszewska-Wiśniewska, Paulina Antosik, 2020

机译：免疫组织化学和实时PCR基司法瘤甘细胞瘤和紫叶叶细胞瘤中BRAF V600E突变的检测

Role of diffusion weighted imaging for differentiating cerebral pilocytic astrocytoma and ganglioglioma BRAF V600E-mutant from wild type

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