A New Taxane Diterpenoid and a New Neolignan from Taxus baccata

摘要

Two new compounds, baccataxinine (1) and baccalignan (2), were isolated from the Taxus baccata, together with 16 known ones. Their structures were elucidated by comprehensive spectroscopic analyses of HR-ESI-MS, NMR and IR. Compound 1 is a taxane diterpenoid possessing a rare dioxolane ring between C-1 and C-2, while 2 is the first benzofuran neolignan from this species. Furthermore, they were also evaluated for their a-glucosidase inhibitory activity, but none of them showed considerable inhibitory effects.