Neuroendocrinology: Hypothalamic self-tuning to stress.

摘要

Our hormonal response to stress, which includes the release of gluco-corticoids and catecholamines such as noradrenaline, is normally exquisitely regulated so that we can adapt to stressful experiences in the appropriate way. For example, stress exposure can sensitize the response system to subsequent exposures to stressors, but a negative-feedback mechanism is also in place to prevent excessive activation of the system to subsequent stressful events.