Translational read-through of CTNS nonsense mutations and attenuation of CTNS nonsense-mediated mRNA decay by ELX-02 treatment

Alroy Iris; Shohat Meytal; Eshkar-Oren Idit; Huertas Pedro

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Translational read-through of CTNS nonsense mutations and attenuation of CTNS nonsense-mediated mRNA decay by ELX-02 treatment

机译：CTNS无意义突变的翻译读数和CTNS废话介导的mRNA衰减通过ELX-02治疗衰减

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来源
《Molecular genetics and metabolism 》 |2018年第2期| 共1页
作者
Alroy Iris; Shohat Meytal; Eshkar-Oren Idit; Huertas Pedro;
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作者单位

Eloxx Pharmaceut Waltham MA USA;

Eloxx Pharmaceut Waltham MA USA;

Eloxx Pharmaceut Waltham MA USA;

Eloxx Pharmaceut Waltham MA USA;

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原文格式 PDF
正文语种 eng
中图分类内分泌腺疾病及代谢病 ;
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1. Translational read-through of CTNS nonsense mutations and attenuation of CTNS nonsense-mediated mRNA decay by ELX-02 treatment [J] . Alroy Iris, Shohat Meytal, Eshkar-Oren Idit, Molecular genetics and metabolism . 2018 ,第2期

机译：CTNS无意义突变的翻译读数和CTNS废话介导的mRNA衰减通过ELX-02治疗衰减
2. Resistance of mRNAs with AUG-proximal nonsense mutations to nonsense-mediated decay reflects variables of mRNA structure and translational activity [J] . Pereira Francisco J. C., Teixeira Alexandre, Kong Jian, Nucleic Acids Research . 2015 ,第13期

机译：具有AUG近端无义突变的mRNA对无义介导的衰变的抗性反映了mRNA结构和翻译活性的变量
3. Resistance of mRNAs with AUG-proximal nonsense mutations to nonsense-mediated decay reflects variables of mRNA structure and translational activity [J] . Alexandre Teixeira, Ana Luísa Silva, Ana Marques-Ramos, Nucleic acids research . 2015 ,第13期

机译：具有AUG近端无义突变的mRNA对无义介导的衰变的抗性反映了mRNA结构和翻译活性的变量
4. Widespread predicted nonsense-mediated mRNA decay of alternatively-spliced transcripts of human normal and disease genes [C] . Richard E. Green, Benjamin P. Lewis, R. Tyler Hillman, International Conference on Intelligent Systems for Molecular biology . 2003

机译：普遍预测的无意义介导的mRNA衰减的人正常和疾病基因的替代剪接转录物
5. No Nonsense: The Protection of Wild-Type mRNAs From Nonsense-Mediated mRNA Decay in Saccharomyces cerevisiae. [D] . Patefield, Krista D. 2016

机译：没有废话：酿酒酵母中的无意义介导的mRNA衰变对野生型mRNA的保护。
6. Resistance of mRNAs with AUG-proximal nonsense mutations to nonsense-mediated decay reflects variables of mRNA structure and translational activity [O] . Francisco J.C. Pereira, Alexandre Teixeira, Jian Kong, 2015

机译：具有AUG近端无义突变的mRNA对无义介导的衰变的抗性反映了mRNA结构和翻译活性的变量
7. Resistance of mRNAs with AUG-proximal nonsense mutations to nonsense-mediated decay reflects variables of mRNA structure and translational activity. [O] . Pereira Francisco, Kong Jian, Siva Ana Luísa, 2015

机译：具有AUG近端无义突变的mRNA对无义介导的衰变的抗性反映了mRNA结构和翻译活性的变量。

Translational read-through of CTNS nonsense mutations and attenuation of CTNS nonsense-mediated mRNA decay by ELX-02 treatment

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