首页> 外文期刊>European Journal of Surgical Oncology: The Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology >shRNA-mediated inhibition of PhosphoGlycerate Kinase 1 (PGK1) enhances cytotoxicity of intraperitoneal chemotherapy in peritoneal metastasis of gastric origin
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shRNA-mediated inhibition of PhosphoGlycerate Kinase 1 (PGK1) enhances cytotoxicity of intraperitoneal chemotherapy in peritoneal metastasis of gastric origin

机译:ShRNA介导的磷酸糖激酶1(PGK1)的抑制增强了胃来源腹膜转移中腹腔化疗的细胞毒性

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摘要

Background: Phosphoglycerate kinase 1 (PGK1) plays metabolic, kinase and translational roles in Peritoneal metastasis (PM) of gastric origin and is associated with chemoresistance. Silencing PGK1 might potentiate the effect of chemotherapy.
机译:背景:磷酸性激酶1(PGK1)在胃来源的腹膜转移(PM)中起代谢,激酶和平移作用,并与化学化相关。 沉默PGK1可能会使化疗的影响提高。

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