Synthesis of a new alkynylated deoxyadenosine phosphoramidite for the click reaction-mediated DNA labeling

Wang Shiyu; Liu Feifan; Fang Jiaobing; Li Yashu; Liu Jun; Liu Mingzhe

首页> 外文期刊>Mendeleev Communications >Synthesis of a new alkynylated deoxyadenosine phosphoramidite for the click reaction-mediated DNA labeling

【24h】

Synthesis of a new alkynylated deoxyadenosine phosphoramidite for the click reaction-mediated DNA labeling

机译：用于咔哒反应介导的DNA标记的新型醇烷基化脱氧糖苷磷酰胺胺的合成

获取原文

获取原文并翻译 | 示例

获取外文期刊封面目录资料

开具论文收录证明 >>

文献代查 >>

文献数据库（团队版） >>

页面导航

摘要
著录项
引文网络
相似文献
相关主题

摘要

A new 5'-dimethoxytrityl N-6-alkynylated 2'-deoxyadenosine phosphoramidite has been designed and synthesized from 2'-deoxyadenosine. The applicability of this building block for the production of alkyne-modified oligodeoxynucleotide has been demonstrated. This allows one to introduce various labels into DNA using the click reaction.

机译：新的5'-二甲氧基蓖麻油N-6-醇盐化2'-脱氧腺苷磷酰胺氨基胺由2'-脱氧腺苷设计和合成。已经证实了该构建块对炔烃改性寡核苷酸生产的适用性。这允许使用单击反应将各种标签引入DNA中。

著录项

来源
《Mendeleev Communications》 |2019年第5期|共3页
作者
Wang Shiyu; Liu Feifan; Fang Jiaobing; Li Yashu; Liu Jun; Liu Mingzhe;
展开▼
作者单位

Shenyang Pharmaceut Univ Sch Pharmaceut Engn Dept Organ Chem Shenyang 110016 Liaoning Peoples R China;

Shenyang Pharmaceut Univ Sch Pharmaceut Engn Dept Organ Chem Shenyang 110016 Liaoning Peoples R China;

Shenyang Pharmaceut Univ Sch Pharmaceut Engn Dept Organ Chem Shenyang 110016 Liaoning Peoples R China;

Shenyang Pharmaceut Univ Sch Pharmaceut Engn Dept Organ Chem Shenyang 110016 Liaoning Peoples R China;

Shenyang Pharmaceut Univ Sch Pharmaceut Engn Dept Organ Chem Shenyang 110016 Liaoning Peoples R China;

Shenyang Pharmaceut Univ Sch Pharmaceut Engn Dept Organ Chem Shenyang 110016 Liaoning Peoples R China;

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类化学;
关键词

相似文献

外文文献
中文文献
专利

1. Synthesis of a new alkynylated deoxyadenosine phosphoramidite for the click reaction-mediated DNA labeling [J] . Wang Shiyu, Liu Feifan, Fang Jiaobing, Mendeleev Communications . 2019,第5期

机译：用于咔哒反应介导的DNA标记的新型醇烷基化脱氧糖苷磷酰胺胺的合成
2. Site-Directed Spin-Labeling of DNA by the Azide–Alkyne ‘Click’ Reaction: Nanometer Distance Measurements on 7-Deaza-2′-deoxyadenosine and 2′-Deoxyuridine Nitroxide Conjugates Spatially Separated or Linked to a ‘dA-dT’ Base Pair [J] . Ping Ding, Dorith Wunnicke, Prof. Heinz-Juuml, Chemistry - A European Journal . 2010,第48期

机译：叠氮基-炔烃“点击”反应对DNA进行定点旋转标记：在7-脱氮基2'-脱氧腺苷和2'-脱氧尿苷一氧化氮上的纳米距离测量在空间上与“ dA-dT”碱基对缀合
3. Synthesis and characterization of phenothiazine labeled oligodeoxynucleotides:novel 2'-deoxyadenosine and thymidine probes for labeling DNA [J] . Xi Hu, Mark W.Grinstaff Bioconjugate Chemistry . 2002,第1期

机译：亚苯甲酸核核苷酸的合成与表征：用于标记DNA的新型2'-脱氧腺苷和胸苷探针
4. ALKYNYLATED CELLULOSE FIBERS(ACFS):A VERSATILE CLICKABLE PLATFORM FOR PREPARATION OF FUNCTIONAL BIOMATERIALS [C] . Chunyue Ding, Lijian Sun, Guifa Xiao, 第五届制浆造纸新技术国际研讨会（ISETPP）暨第三届国际造纸与环境学术大会（IPEC）论文集 . 2016

机译：烷基化纤维素纤维（ACFS）：多功能可点击平台，用于制备功能性生物材料
5. DNA minor groove modifications: Synthesis and application of 3-deaza-3-substituted-2'-deoxyadenosine analogues [D] . Salandria, Kerry J. 2011

机译：DNA小沟修饰：3-deaza-3-取代-2'-deoxyadenosine类似物的合成和应用
6. Synthesis of a thymidine phosphoramidite labelled with 13C at C6: relaxation studies of the loop region in a 13C labelled DNA hairpin. [O] . J R Williamson, S G Boxer 1988

机译：在C6用13C标记的胸苷亚磷酰胺的合成：13C标记的DNA发夹中环区的松弛研究。
7. Phosphoramidite building blocks with protected nitroxides for the synthesis of spin-labeled DNA and RNA [O] . Timo Weinrich, Eva A Jaumann, Ute M Scheffer, 2018

机译：具有受保护的硝基氧化物的磷酰胺岩结构块，用于合成旋转标记的DNA和RNA

Synthesis of a new alkynylated deoxyadenosine phosphoramidite for the click reaction-mediated DNA labeling

摘要

著录项

引文网络

相似文献

相关主题

期刊订阅