Fibroblast growth factor 21 in cardio-metabolic disorders: a systematic review and meta-analysis

Lakhani Ishan; Gong Mengqi; Wong Wing Tak; Bazoukis George; Lampropoulos Konstantinos; Wong Sunny Hei; Wu William K. K.; Wong Martin C. S.; Ong Kwok-Leung; Liu Tong; Tse Gary

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Fibroblast growth factor 21 in cardio-metabolic disorders: a systematic review and meta-analysis

机译：心肌代谢障碍的成纤维细胞生长因子21：系统评价和荟萃分析

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Background: Fibroblast growth factor 21 is a signalling protein involved in cell differentiation, morphogenesis, proliferation and metabolism. Recent studies have associated increased levels of FGF21 in the development of cardiovascular diseases, whereas others have reported no significant associations. Therefore, this systematic review and meta-analysis evaluated the value in predicting the risk of cardio-metabolic disorders and mortality.

机译：背景：成纤维细胞生长因子21是参与细胞分化，形态发生，增殖和代谢的信号蛋白。最近的研究在心血管疾病发展中有相关的FGF21水平，而其他研究则报告没有重大协会。因此，这种系统审查和荟萃分析评估了预测心肌代谢障碍和死亡率风险的价值。

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来源
《Metabolism: Clinical and Experimental》 |2018年第2018期|共7页
作者
Lakhani Ishan; Gong Mengqi; Wong Wing Tak; Bazoukis George; Lampropoulos Konstantinos; Wong Sunny Hei; Wu William K. K.; Wong Martin C. S.; Ong Kwok-Leung; Liu Tong; Tse Gary;
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作者单位

Chinese Univ Hong Kong Dept Med &

Therapeut Fac Med Hong Kong Hong Kong Peoples R China;

Tianjin Med Univ Tianjin Inst Cardiol Tianjin Key Lab Ion Mol Funct Cardiovasc Dis Dept Cardiol;

Chinese Univ Hong Kong Sch Life Sci Hong Kong Hong Kong Peoples R China;

Evangelismos Gen Hosp Athens Dept Cardiol 2 Lab Cardiac Electrophysiol Athens Greece;

Evangelismos Gen Hosp Athens Dept Cardiol 2 Lab Cardiac Electrophysiol Athens Greece;

Chinese Univ Hong Kong Dept Med &

Therapeut Fac Med Hong Kong Hong Kong Peoples R China;

Chinese Univ Hong Kong Li Ka Shing Inst Hlth Sci Fac Med Hong Kong Hong Kong Peoples R China;

Chinese Univ Hong Kong Fac Med Jockey Club Sch Publ Hlth &

Primary Hong Kong Hong Kong Peoples;

Univ New South Wales Sch Med Sci Fac Med Sydney NSW Australia;

Tianjin Med Univ Tianjin Inst Cardiol Tianjin Key Lab Ion Mol Funct Cardiovasc Dis Dept Cardiol;

Chinese Univ Hong Kong Dept Med &

Therapeut Fac Med Hong Kong Hong Kong Peoples R China;

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原文格式 PDF
正文语种 eng
中图分类内分泌腺疾病及代谢病;
关键词
Fibroblast growth factor 21; FGF21; Coronary artery disease; Metabolic syndrome; Diabetes mellitus; Mortality;

机译：成纤维细胞生长因子21;FGF21;冠状动脉疾病;代谢综合征;糖尿病;死亡率;

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专利

1. Fibroblast growth factor 21 in cardio-metabolic disorders: a systematic review and meta-analysis [J] . Lakhani Ishan, Gong Mengqi, Wong Wing Tak, Metabolism: Clinical and Experimental . 2018,第期

机译：心肌代谢障碍的成纤维细胞生长因子21：系统评价和荟萃分析
2. Association of wrist circumference with cardio-metabolic risk factors: a systematic review and meta-analysis [J] . Zeitschrift fur Arznei- und Gewurzpflanzen . 2020,第1期

机译：腕围与心脏代谢危险因素的协会：系统评价和荟萃分析
3. Association of wrist circumference with cardio-metabolic risk factors: a systematic review and meta-analysis [J] . Namazi Nazli, Djalalinia Shirin, Mahdavi-Gorabi Armita, Eating and weight disorders: EWD . 2020,第1期

机译：腕围与心脏代谢危险因素的协会：系统评价和荟萃分析
4. A SYSTEMATIC REVIEW AND META-ANALYSIS OF LOWER BACK DISORDERS AMONG HEAVY EQUIPMENT OPERATORS [C] . Mbulelo Makola, Ash Genaidy Ergonomics Society Annual Conference; 200604; Robinson College Cambridge(GB) . 2006

机译：大型设备运营商中下背部疾病的系统评价和元分析
5. The Role of Reproductive Risk Factors in Hereditary Breast Cancer Within BRCA Mutation Carriers: Systematic Review and Meta-Analysis [D] . Springer, Tamara. 2021

机译：BRCA突变载体中生殖危险因素在遗传性乳腺癌中的作用：系统评价和荟萃分析
6. Dynamics and Distribution of Klothoβ (KLB) and Fibroblast Growth Factor Receptor-1 (FGFR1) in Living Cells Reveal the Fibroblast Growth Factor-21 (FGF21)-induced Receptor Complex [O] . Aaron Y. K. Ming, Eunjong Yoo, Eugene N. Vorontsov, 2012

机译：活细胞中Klothoβ（KLB）和成纤维细胞生长因子受体1（FGFR1）的动力学和分布揭示了成纤维细胞生长因子21（FGF21）诱导的受体复合物。
7. Increased serum/plasma fibroblast growth factor 21 in type 2 diabetes mellitus: a systematic review and meta-analysis [O] . Yun-Sheng Wang, Jun Ye, Yong-Hong Cao, 2019

机译：增加血清/血浆成纤维细胞生长因子21在2型糖尿病中：系统评价和荟萃分析

Fibroblast growth factor 21 in cardio-metabolic disorders: a systematic review and meta-analysis

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