Pentraxin 3 Is Closely Associated With Tubulointerstitial Injury in Lupus Nephritis A Large Multicenter Cross-Sectional Study

摘要

Lupus nephritis always elicits immune inflammatory tissue damages in kidney. Pentraxin 3 (PTX3), mainly produced at inflammatory sites, is known to be involved in the regulation of the innate immunity system. The aim of this study was to investigate the serum and urine levels of PTX3, and the expression of PTX3 in renal tissues in lupus nephritis patients from a large Chinese cohort.