Exploring Spatial Overlap of High-Uptake Regions Derived From Dual Tracer Positron Emission Tomography-Computer Tomography Imaging Using F-18-Fluorodeoxyglucose and F-18-Fluorodeoxythymidine in Nonsmall Cell Lung Cancer Patients A Prospective Pilot Study

摘要

Interest is growing in radiotherapy to nonuniformly boost radioresistant regions within nonsmall cell lung cancer (NSCLC) using molecular imaging techniques. The complexity of tumor behavior is beyond the ability of any single radiotracer to reveal. We hold dual tracer positron emission tomography-computer tomography (PET/CT) imaging with fluorodeoxyglucose (FDG) and fluorodeoxythymidine (FLT) for NSCLC patients to offer an integrated overlook of tumor biological behaviors quantitatively and localizationally, which may help biological target volume delineation and subvolume boost.