首页> 外文期刊>Medical dosimetry: official journal of the American Association of Medical Dosimetrists >Assessing dose variance from immobilization devices in VMAT head and neck treatment planning: A retrospective case study analysis
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Assessing dose variance from immobilization devices in VMAT head and neck treatment planning: A retrospective case study analysis

机译:评估VMAT头部和颈部治疗规划中的固定装置的剂量方差:回顾性案例研究分析

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Immobilization devices serve several purposes in radiation oncology including improved positional reproducibility and decreased patient movement. If immobilization device beam attenuation is unaccounted for in the treatment planning process, planning target volume (PTV) coverage can be compromised. A retrospective case study was performed to evaluate beam attenuation from head and neck (HN) immobilization devices in volumetric modulated arc therapy using the Eclipse treatment planning system and the Anisotropic Analytical Algorithm. Three facilities retrospectively evaluated 15 patients with various HN carcinomas. A test plan was created from each patient's existing plan in Eclipse to include immobilization devices in the dose calculation. Plan comparisons were performed using dose volume histograms, which assessed the maximum dose, percentage of the PTV that received 95% of the prescription dose (V-95), and dose covering 100% of the PTV (D-100). The test plan normalization values were then adjusted to match the original PTV coverage. The maximum dose difference calculated ranged from 0.3% to 4.1%. The absolute difference in V-95 coverage between the HN and the test plans ranged from 0.4% to 2.3%. The difference in the D-100 was more statistically significant, reporting a range of 1.2% to 71.4%. Finally, to achieve the same PTV coverage as observed in the HN plan, an adjustment to the normalization value was needed, which required a change ranging from 0.1 to 7.7. Attenuation from immobilization devices, when unaccounted for, can cause a misrepresentation of the dose delivered to the PTV. It is not a standardized practice among institutions to include immobilization devices within the body contour for dose calculations. However, with the increasing use of volumetric modulated arc therapy for treatment of the HN region, precision is of the utmost importance, and inclusion of immobilization devices should be standardized. (C) 2017 American Association of Medical Dosimetrists.
机译:固定装置在放射肿瘤学中有几种目的,包括改善的位置再现性和降低的患者运动。如果在治疗计划过程中未考虑固定装置光束衰减,则可能会损害计划目标体积(PTV)覆盖范围。进行了回顾性案例研究以评估使用Eclipse治疗计划系统和各向异性分析算法在体积调制的电弧疗法中的头部和颈部(HN)固定装置的光束衰减。三个设施回顾性评估了15名患有各种HN癌的患者。从每位患者的现有计划中创建测试计划,以包括剂量计算中的固定装置。使用剂量体积直方图进行计划比较,其评估最大剂量,接受95%的处方剂量(V-95)的PTV百分比,以及覆盖PTV(D-100)的100%的剂量。然后调整测试计划标准化值以匹配原始PTV覆盖范围。计算的最大剂量差异范围为0.3%至4.1%。 HN与测试计划之间的V-95覆盖率的绝对差异范围为0.4%至2.3%。 D-100的差异更为统计学意义,报告的范围为1.2%至71.4%。最后,为了在HN计划中观察到的相同的PTV覆盖,需要对归一化值进行调整,这需要改变0.1至7.7。从固定装置衰减,当未负责的情况下,可能导致递送给PTV的剂量的虚假陈述。在机构中包括用于剂量计算的固定装置的机构中的标准化实践。然而,随着越来越多地使用用于治疗HN区域的体积调制电弧疗法,精确度至关重要,并且应标准化固定装置的包含。 (c)2017年美国医疗剂量分子协会。

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