Rapid and Robust Variable Flip Angle T-1 Mapping Using Interleaved Two-Dimensional Multislice Spoiled Gradient Echo Imaging

摘要

Purpose: Conventional T-1 mapping using three-dimensional (3D) radiofrequency (RF) spoiled gradient echo (SPGR) imaging with short repetition times (TR) is adversely affected by incomplete spoiling (i.e. residual T-2 dependency). In this work, an optimized interleaved 2D multislice SPGR sequence scheme and an adapted postprocessing procedure are evaluated for highly T-2-insensitive T-1 quantification of human brain tissues.