Diagnostic and prognostic significance of serum CD26 level in Asian women with high-grade serous ovarian carcinoma

摘要

Aim: The aim of this study was to reveal the diagnostic and prognostic significance of serum CD26 level in high-grade serous ovarian carcinoma women in China. Methods: There were 229 high-grade serous ovarian carcinomawomen and 365 controls. Baseline serum CD26 level was measured using ELISA. A36-month post-operation follow-up was performed. Results: Baseline serum CD26 level <= 601.5pg/ml was associated with the increased risk of ovarian carcinoma (OR: 1.67; 95% CI: 1.20-2.32). Baseline serum level of CD26 <= 589.7pg/ml was related to the elevated risk of cancer death (HR: 1.33; 95% CI: 1.04-1.69). Conclusion: Baseline serum CD26 level might be an independent diagnostic and prognostic marker for high-grade serous ovarian carcinoma.