Comprehensive transcriptome analysis identifies pathways with therapeutic potential in locally advanced cervical cancer

Campos-Parra Alma Delia; Padua-Bracho Alejandra; Pedroza-Torres Abraham; Figueroa-Gonzalez Gabriela; Fernandez-Retana Jorge; Millan-Catalan Oliver; Peralta-Zaragoza Oscar; de Leon David Cantu; Herrera Luis A.; Perez-Plasencia Carlos

首页> 外文期刊>Gynecologic Oncology: An International Journal >Comprehensive transcriptome analysis identifies pathways with therapeutic potential in locally advanced cervical cancer

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Comprehensive transcriptome analysis identifies pathways with therapeutic potential in locally advanced cervical cancer

机译：综合转录组分析鉴定局部晚期宫颈癌治疗潜力的途径

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摘要

Objective. The objective of the present study was to provide genomic and transcriptomic information that may improve clinical outcomes for locally advanced cervical cancer (LACC) patients by searching for therapeutic targets or potential biomarkers through the analysis of significantly altered signaling pathways in LACC.

机译：客观的。本研究的目的是提供基因组和转录组信息，可通过分析LACC中显着改变的信号通路来搜索治疗靶标或潜在的生物标志物来改善局部晚期宫颈癌（LACC）患者的临床结果。

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来源
《Gynecologic Oncology: An International Journal》 |2016年第2期|共8页
作者
Campos-Parra Alma Delia; Padua-Bracho Alejandra; Pedroza-Torres Abraham; Figueroa-Gonzalez Gabriela; Fernandez-Retana Jorge; Millan-Catalan Oliver; Peralta-Zaragoza Oscar; de Leon David Cantu; Herrera Luis A.; Perez-Plasencia Carlos;
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Inst Nacl Cancerol INCan Lab Genom Ave San Fernando 22 Col Secc 16 Mexico City 14080 DF Mexico;

Inst Nacl Cancerol INCan Lab Genom Ave San Fernando 22 Col Secc 16 Mexico City 14080 DF Mexico;

Inst Nacl Cancerol INCan Lab Genom Ave San Fernando 22 Col Secc 16 Mexico City 14080 DF Mexico;

Inst Nacl Cancerol INCan Lab Genom Ave San Fernando 22 Col Secc 16 Mexico City 14080 DF Mexico;

Inst Nacl Cancerol INCan Lab Genom Ave San Fernando 22 Col Secc 16 Mexico City 14080 DF Mexico;

Inst Nacl Cancerol INCan Lab Genom Ave San Fernando 22 Col Secc 16 Mexico City 14080 DF Mexico;

Inst Nacl Salud Publ Direcc Infecc Cron &

Canc Cuernavaca 62100 Morelos Mexico;

Inst Nacl Cancerol INCan Unidad Invest Biomed Canc Ave San Fernando 22 Col Secc 16 Mexico City;

Inst Nacl Cancerol INCan Unidad Invest Biomed Canc Ave San Fernando 22 Col Secc 16 Mexico City;

Inst Nacl Cancerol INCan Lab Genom Ave San Fernando 22 Col Secc 16 Mexico City 14080 DF Mexico;

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原文格式 PDF
正文语种 eng
中图分类肿瘤学;
关键词
Locally advanced cervical cancer; Genomic and transcriptome analysis; Therapeutic targets;

机译：局部晚期宫颈癌;基因组和转录组分析;治疗目标;

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专利

1. Comprehensive transcriptome analysis identifies pathways with therapeutic potential in locally advanced cervical cancer [J] . Campos-Parra Alma Delia, Padua-Bracho Alejandra, Pedroza-Torres Abraham, Gynecologic Oncology: An International Journal . 2016,第2期

机译：全面的转录组分析可确定局部晚期宫颈癌具有治疗潜力的途径
2. Pan-Cancer Analysis of the Mediator Complex Transcriptome Identifies CDK19 and CDK8 as Therapeutic Targets in Advanced Prostate Cancer [J] . Braegelmann Johannes, Kluemper Niklas, Offermann Anne, Clinical cancer research: an official journal of the American Association for Cancer Research . 2017,第7期

机译：介质复合体转录组的泛癌分析将CDK19和CDK8鉴定为晚期前列腺癌中的治疗靶标
3. Comprehensive analysis of patient outcome after local recurrence of locally advanced cervical cancer treated with concomitant chemoradiation and image-guided adaptive brachytherapy [J] . Mignot F., Gouy S., Schernberg A., Gynecologic Oncology: An International Journal . 2020,第3期

机译：伴随校长治疗局部晚期宫颈癌局部复发后患者结果的综合分析及图像引导式自适应近距离放射治疗
4. Quantitative Pathway Analysis of Basal Breast Cancer Cell Line Proteomes Reveals Signaling Features, Potential Therapeutic Targets [C] . Atim A. Enyenihi, Therese Hemstrom, Roman A. Zubarev American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2012

机译：基础乳腺癌细胞系蛋白质组的定量途径分析显示信号传导特征，潜在的治疗目标
5. Adaptive Radiation Therapy Planning Using Fluorodeoxyglucose PET -- Locally Advanced Cervical Cancer. [D] . Mehta, Par. 2011

机译：使用氟脱氧葡萄糖PET进行的适应性放射治疗计划-局部晚期宫颈癌。
6. Therapeutic value of surgical paraaortic staging in locally advanced cervical cancer: a multicenter cohort analysis from the FRANCOGYN study group [O] . Yohann Dabi, Vanille Simon, Xavier Carcopino, 2018

机译：手术后主动脉分期对局部晚期宫颈癌的治疗价值：FRANCOGYN研究组的多中心队列分析
7. Comprehensive transcriptome analysis identifies pathways with therapeutic potential in locally advanced cervical cancer [O] . Campos-Parra Alma Delia, Padua-Bracho Alejandra, Pedroza-Torres Abraham, 2016

机译：全面的转录组分析可确定局部晚期宫颈癌具有治疗潜力的途径

Comprehensive transcriptome analysis identifies pathways with therapeutic potential in locally advanced cervical cancer

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