MED12 mutation frequency in unselected sporadic uterine leiomyomas

Heinonen Hanna-Riikka; Sarvilinna Nanna S.; Sjoberg Jari; Kampjarvi Kati; Pitkanen Esa; Vahteristo Pia; Makinen Netta; Aaltonen Lauri A.

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MED12 mutation frequency in unselected sporadic uterine leiomyomas

机译：未选择的孢子子子宫内肌瘤中的Med12突变频率

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摘要

Objective: To determine the frequency of mediator complex subunit 12 (MED12) mutations in well-documented, prospectively collected, unselected series of sporadic uterine leiomyomas to better understand the contribution of MED12 mutations in leiomyoma genesis.

机译：目的：确定介质复合亚基12（MED12）突变在齐全，预期收集的，未选择的，未选择的一系列散发性子宫平滑肌瘤中的频率，以更好地了解MED12突变在平滑肌瘤起源中的贡献。

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来源
《Fertility and Sterility: Official Journal of the American Fertility Society, Pacific Coast Fertility Society, and the Canadian Fertility and Andrology Society》 |2014年第4期|共6页
作者
Heinonen Hanna-Riikka; Sarvilinna Nanna S.; Sjoberg Jari; Kampjarvi Kati; Pitkanen Esa; Vahteristo Pia; Makinen Netta; Aaltonen Lauri A.;
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作者单位

Univ Helsinki Dept Med Genet Helsinki 00014 Finland;

Univ Helsinki Res Programs Unit Genome Scale Biol Res Program FIN-00014 Helsinki Finland;

Univ Helsinki Cent Hosp Dept Obstet &

Gynecol Helsinki 00014 Finland;

Univ Helsinki Dept Med Genet Helsinki 00014 Finland;

Univ Helsinki Dept Med Genet Helsinki 00014 Finland;

Univ Helsinki Dept Med Genet Helsinki 00014 Finland;

Univ Helsinki Dept Med Genet Helsinki 00014 Finland;

Univ Helsinki Dept Med Genet Helsinki 00014 Finland;

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原文格式 PDF
正文语种 eng
中图分类妇科学;
关键词
Fibroids; genetics; MED12; uterine leiomyomas;

机译：肌瘤;遗传学;Med12;子宫leiomyomas;

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专利

1. MED12 mutation frequency in unselected sporadic uterine leiomyomas [J] . Heinonen Hanna-Riikka, Sarvilinna Nanna S., Sjoberg Jari, Fertility and Sterility: Official Journal of the American Fertility Society, Pacific Coast Fertility Society, and the Canadian Fertility and Andrology Society . 2014,第4期

机译：未选择的散发性子宫平滑肌瘤中的MED12突变频率
2. Frequency and Spectrum of MED12 Exon 2 Mutations in Multiple Versus Solitary Uterine Leiomyomas From Russian Patients [J] . Osinovskaya Natalia S., Malysheva Olga V., Shved Natalia Yu., International journal of gynecological pathology: Official journal of the International Society of Gynecological Pathologists . 2016,第6期

机译：俄罗斯患者多发性孤立性子宫平滑肌瘤中MED12外显子2突变的频率和频谱
3. Low frequency of somatic mutations in the FH/multiple cutaneous leiomyomatosis gene in sporadic leiomyosarcomas and uterine leiomyomas [J] . K T Barker, S Bevan, R Wang, British Journal of Cancer . 2002,第4期

机译：散发性平滑肌肉瘤和子宫平滑肌瘤的FH /多发性皮肤平滑肌瘤基因中的体细胞突变频率较低
4. EFFECT OF DOSE, TIMING AND DELIVERY OF TUMOR NECROSIS FACTOR ALPHA AS A CRYOADJUVANT IN CRYOSURGERY OF ELT-3 UTERINE LEIOMYOMA (FIBROID) TUMOR [C] . Jing Jiang, John Bischof ASME summer bioengineering conference;SBC2009 . 2009

机译：肿瘤坏死因子α的剂量，时机和递送在CRT手术中对ELT-3子宫平滑肌瘤（类固醇）肿瘤的冷辅助作用
5. A Novel Molecular Pathway Involving GPR10, REST, and PRICKLE1 in the Pathogenesis of Uterine Leiomyoma. [D] . McWilliams, Michelle Marie. 2017

机译：子宫平滑肌瘤发病机制中涉及GPR10，REST和PRICKLE1的新型分子途径。
6. Low frequency of somatic mutations in the FH/multiple cutaneous leiomyomatosis gene in sporadic leiomyosarcomas and uterine leiomyomas [O] . K T Barker, S Bevan, R Wang, 2002

机译：散发性平滑肌肉瘤和子宫平滑肌瘤的FH /多发性皮肤平滑肌瘤基因中的体细胞突变频率较低
7. Low frequency of somatic mutations in the FH/multiple cutaneous leiomyomatosis gene in sporadic leiomyosarcomas and uterine leiomyomas [O] . Barker, K T, Bevan, S, Wang, R, 2002

机译：散发性平滑肌肉瘤和子宫平滑肌瘤的FH /多发性皮肤平滑肌瘤基因中的体细胞突变频率较低

MED12 mutation frequency in unselected sporadic uterine leiomyomas

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