Responsiveness of histological disease activity indices in ulcerative colitis: a post hoc analysis using data from the TOUCHSTONE randomised controlled trial

Jairath Vipul; Peyrin-Biroulet Laurent; Zou Guangyong; Mosli Mahmoud; Vande Casteele Niels; Pai Reetesh K.; Valasek Mark A.; Marchal-Bressenot Aude; Stitt Larry W.; Shackelton Lisa M.; Khanna Reena; DHaens Geert R.; Sandborn William J.; Olson Allan; Feagan Brian G.; Pai Rish K.

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Responsiveness of histological disease activity indices in ulcerative colitis: a post hoc analysis using data from the TOUCHSTONE randomised controlled trial

机译：溃疡性结肠炎组织学疾病活动指标的反应性：使用来自Rogionstone随机对照试验的数据的后HOC分析

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摘要

Objective We evaluated the reliability and responsiveness of available but incompletely validated UC histological disease activity indices using standardised rules for centralised assessment.

机译：目的，我们评估了可用但不完全验证的UC组织学疾病活动指数的可靠性和响应性，用于使用标准化的集中评估规则。

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《Gut: Journal of the British Society of Gastroenterology》 |2019年第7期|共7页
作者
Jairath Vipul; Peyrin-Biroulet Laurent; Zou Guangyong; Mosli Mahmoud; Vande Casteele Niels; Pai Reetesh K.; Valasek Mark A.; Marchal-Bressenot Aude; Stitt Larry W.; Shackelton Lisa M.; Khanna Reena; DHaens Geert R.; Sandborn William J.; Olson Allan; Feagan Brian G.; Pai Rish K.;
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作者单位

Robarts Clin Trials Inc London ON Canada;

Lorraine Univ Dept Gastroenterol Vandoeuvre Les Nancy France;

Robarts Clin Trials Inc London ON Canada;

King Abdulaziz Univ Dept Med Jeddah Saudi Arabia;

Robarts Clin Trials Inc London ON Canada;

Univ Pittsburgh Med Ctr Dept Pathol Pittsburgh PA USA;

Univ Calif San Diego Dept Pathol La Jolla CA 92093 USA;

Univ Reims &

Champagne Ardenne Dept Pathol Reims France;

Robarts Clin Trials Inc London ON Canada;

Robarts Clin Trials Inc London ON Canada;

Robarts Clin Trials Inc London ON Canada;

Robarts Clin Trials Inc London ON Canada;

Robarts Clin Trials Inc London ON Canada;

Celgene San Diego CA USA;

Robarts Clin Trials Inc London ON Canada;

Mayo Clin Dept Lab Med &

Pathol Scottsdale AZ USA;

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正文语种 eng
中图分类消化系及腹部疾病;
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1. Responsiveness of histological disease activity indices in ulcerative colitis: a post hoc analysis using data from the TOUCHSTONE randomised controlled trial [J] . Jairath Vipul, Peyrin-Biroulet Laurent, Zou Guangyong, Gut: Journal of the British Society of Gastroenterology . 2019,第7期

机译：溃疡性结肠炎组织学疾病活动指标的反应性：使用来自Rogionstone随机对照试验的数据的后HOC分析
2. A Simplified Definition of Histologic Improvement in Ulcerative Colitis and its Association With Disease Outcomes up to 30 Weeks from Initiation of Therapy: Post Hoc Analysis of Three Clinical Trials [J] . Li Katherine, Strauss Richard, Marano Colleen, Journal of Crohn’s & colitis . 2019,第8期

机译：溃疡性结肠炎组织学改善的简化定义及其与治疗开始后30周的疾病结果的关系：三次临床试验后的HOC分析
3. Plasma fibrinogen in ulcerative colitis: the effect of disease activity and nicotine therapy in a randomised controlled trial. [J] . Ingram JR, Rhodes J, Collins PW, Digestive and liver disease: official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver . 2005,第11期

机译：溃疡性结肠炎中的血浆纤维蛋白原：在一项随机对照试验中，疾病活性和尼古丁治疗的影响。
4. Synbiotic Therapy Significantly Reduces Molecular Markers of Inflammation and Clinical Scores in Patients with Active Ulcerative Colitis; A Randomised Controlled Trial [C] . Controlled Release Society annual meeting . 2004

机译：同步治疗显着减少了活性溃疡性结肠炎患者的炎症和临床评分的分子标记;随机对照试验
5. Utilization of Propensity Score Weighting and Targeted Maximum Likelihood Estimation in the Post Hoc Analysis of a Randomized Controlled Trial for the Treatment of Cocaine Dependence (NIDA-MDS-Modafinil-0001) [D] . Shan, Weiwei. 2018

机译：倾向评分加权和目标最大似然估计在可卡因依赖治疗随机对照试验事后分析中的应用（NIDA-MDS-Modafinil-0001）
6. Are we drawing the right conclusions from randomised placebo-controlled trials? A post-hoc analysis of data from a randomised controlled trial [O] . M Diana van Die, Kerry M Bone, Henry G Burger, 2009

机译：我们是否从随机安慰剂对照试验中得出正确的结论？对来自随机对照试验的数据进行事后分析
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Responsiveness of histological disease activity indices in ulcerative colitis: a post hoc analysis using data from the TOUCHSTONE randomised controlled trial

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