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Potentially inappropriate medications in Chinese older adults: The beers criteria compared with the screening tool of older persons’ prescriptions criteria

机译:中国老年人的潜在药物:贝尔斯标准与老年人处方标准的筛选工具相比

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摘要

Aim The present study aimed to assess the prevalence of potentially inappropriate medications (PIM) use in West China Hospital residents aged ≥65 years, using two sets of criteria – the Beers and Screening Tool of Older Persons’ Prescriptions (STOPP) criteria – and to compare the Beers and STOPP criteria, and to determine the better criteria for assessing PIM of older adults in China. Methods This was a retrospective cross‐sectional study, and all patients were aged ≥65 years and admitted through the Information Center of West China Hospital from October 2010 to April 2013. The Beers and STOPP criteria were used to identify PIM. A multivariate logistic regression study was used to identify the predictors of PIM use. Results In the 6337 patients included, the mean age was 81.30 years (SD 6.75), 4795 (75.70%) were male and 5033 (79.42%) were prescribed at least one PIM by either criterion. The Beers criteria identified PIM use in 4593 (72.48%) of patients, and 3278 (51.73%) of patients used at least one PIM according to the STOPP criteria. The most prevalent PIM according to the Beers criteria were benzodiazepines (34.40%); according to the STOPP criteria, it was calcium channel blockers with chronic constipation (18.52%). Increasing age, sex (female), the number of diagnostic diseases and the number of prescribed medications predicted PIM use by both criteria. Conclusion The present study showed a high frequency of PIM in China. The Beers criteria had a higher detection rate and were more sensitive for assessing PIM of older adults in China. Geriatr Gerontol Int 2017; 17: 1951–1958 .
机译:目的,目前的研究旨在评估≥65岁的西部医院居民(PIM)在≥65岁的潜在药物(PIM)的流行,采用两套标准 - 老年人的处方(停止)标准 - 和筛选工具 - 以及比较啤酒和停止标准,并确定中国老年人PIM的更好标准。方法这是回顾性的横截面研究,所有患者均为≥65岁,并通过2010年10月至2013年4月的西部医院信息中心录取。啤酒和停止标准用于识别PIM。使用多变量逻辑回归研究来识别PIM使用的预测因子。结果在包括6337名患者中,平均年龄为81.30岁(SD 6.75),4795(75.70%)是雄性,5033(79.42%)通过标准至少一PIM规定。啤酒标准确定了4593(72.48%)患者的PIM,3278(51.73%)患者根据停止标准使用至少一个PIM。根据贝尔斯标准的最普遍的PIM是苯二氮藻(34.40%);根据停止标准,它是钙通道阻滞剂,具有慢性便秘(18.52%)。增加年龄,性别(女性),诊断疾病的数量和规定药物的数量预测了两个标准的PIM。结论本研究显示了中国的高频PIM。啤酒标准具有更高的检出率,对评估中国老年人PIM更敏感。 Geriadt Gerontol int 2017; 17:1951-1958。

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  • 作者单位

    Department of PharmacyWest China Hospital of Sichuan University and Collaborative Innovation Center;

    Department of PharmacyWest China Hospital of Sichuan University and Collaborative Innovation Center;

    Laboratory of Clinical Pharmacy and Adverse Drug ReactionWest China Hospital of Sichuan University;

    Department of PharmacyWest China Hospital of Sichuan University and Collaborative Innovation Center;

    Department of PharmacyWest China Hospital of Sichuan University and Collaborative Innovation Center;

    Department of PharmacyWest China Hospital of Sichuan University and Collaborative Innovation Center;

    Department of PharmacyWest China Hospital of Sichuan University and Collaborative Innovation Center;

    Department of PharmacyWest China Hospital of Sichuan University and Collaborative Innovation Center;

    Department of PharmacyWest China Hospital of Sichuan University and Collaborative Innovation Center;

    Department of PharmacyWest China Hospital of Sichuan University and Collaborative Innovation Center;

    Department of PharmacyWest China Hospital of Sichuan University and Collaborative Innovation Center;

    The Center of Gerontology and GeriatricsWest China Hospital of Sichuan University and Collaborative;

    Molecular Medicine Research Center State Key Laboratory of Biotherapy and Cancer CenterWest China;

    Department of PharmacyWest China Hospital of Sichuan University and Collaborative Innovation Center;

    Department of PharmacyWest China Hospital of Sichuan University and Collaborative Innovation Center;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 老年病学;
  • 关键词

    Beers; elderly; potentially inappropriate medications; screening tool of older persons’ prescriptions;

    机译:啤酒;老人;可能不恰当的药物;老年人处方的筛选工具;

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