Association between values of preoperative 6-min walk test and surgical outcomes in lung cancer patients with decreased predicted postoperative pulmonary function

摘要

Abstract Objective We retrospectively investigated the possibility that the 6-min walk test (6MWT) could predict surgical outcomes in lung cancer patients with decreased predicted postoperative (ppo) lung function. Methods Patients were enrolled based on their preoperative spirometry: ?10?days, home oxygen therapy (HOT) requirement, unexpected readmission within 90?days, and 90-day mortality were included as surgical outcomes. The correlations with walking distance and the minimum SpO~(2)(SpO~(2)min) and maximum decrease in SpO~(2)(ΔSpO~(2)) during the 6MWT were analyzed using logistic regression analysis, adjusting for age, sex, and surgical procedure. Results Altogether, 121 patients were analyzed. Logistic regression analysis revealed that higher ΔSpO~(2)and lower SpO~(2)min were significantly correlated with a higher risk of prolonged need for oxygen inhalation and HOT, surgical morbidity, and 90-day mortality. Cut-off values of >?4% for ΔSpO~(2)were significant for prolonged oxygen inhalation and surgical morbidity. Cut-off values of Conclusions Oxygen desaturation during 6MWT was a good predictor for poor surgical outcomes in lung cancer patients with decreased ppo pulmonary function.