Subsequent Chemotherapy and Treatment Patterns After Abiraterone Acetate in Patients with Metastatic Castration-resistant Prostate Cancer: Post Hoc Analysis of COU-AA-302

de Bono Johann S.; Smith Matthew R.; Saad Fred; Rathkopf Dana E.; Mulders Peter F. A.; Small Eric J.; Shore Neal D.; Fizazi Karim; De Porre Peter; Kheoh Thian; Li Jinhui; Todd Mary B.; Ryan Charles J.; Flaig Thomas W.

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Subsequent Chemotherapy and Treatment Patterns After Abiraterone Acetate in Patients with Metastatic Castration-resistant Prostate Cancer: Post Hoc Analysis of COU-AA-302

机译：转移阉割前列腺癌患者乙酸乙酯后的后续化疗和治疗模式：CO-AA-302后HOC分析

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Background: Treatment patterns for metastatic castration-resistant prostate cancer (mCRPC) have changed substantially in the last few years. In trial COU-AA-302 (chemotherapy-naive men with mCRPC), abiraterone acetate plus prednisone (AA) significantly improved radiographic progression-free survival and overall survival (OS) when compared to placebo plus prednisone (P).

机译：背景：转移性阉割的前列腺癌（MCRPC）的治疗模式在过去几年中大大变化。在试验COU-AA-302（具有MCRPC的化疗 - 幼稚男性）中，与安慰剂加上泼尼松（P）相比，AbiraTerone醋酸盐加上泼尼松（AA）显着改善了放射性的无进展生存和整体存活（OS）。

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《European urology》 |2017年第4期|共9页
作者
de Bono Johann S.; Smith Matthew R.; Saad Fred; Rathkopf Dana E.; Mulders Peter F. A.; Small Eric J.; Shore Neal D.; Fizazi Karim; De Porre Peter; Kheoh Thian; Li Jinhui; Todd Mary B.; Ryan Charles J.; Flaig Thomas W.;
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作者单位

Inst Canc Res Sutton Surrey England;

Harvard Med Sch Boston MA USA;

Ctr Hosp Univ Montreal Montreal PQ Canada;

Mem Sloan Kettering Canc Ctr 1275 York Ave New York NY 10021 USA;

Radboud Univ Nijmegen Med Ctr Nijmegen Netherlands;

Univ Calif San Francisco Helen Diller Family Comprehens Canc Ctr San Francisco CA 94143 USA;

Atlantic Urol Clin Carolina Urol Res Ctr Myrtle Beach SC USA;

Univ Paris Sud Inst Gustave Roussy Villejuif France;

Janssen Res &

Dev Beerse Belgium;

Janssen Res &

Dev San Diego CA USA;

Johnson &

Johnson Med China Shanghai Peoples R China;

Janssen Global Serv Raritan NJ USA;

Univ Calif San Francisco Helen Diller Family Comprehens Canc Ctr San Francisco CA 94143 USA;

Univ Colorado Ctr Canc Aurora CO USA;

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原文格式 PDF
正文语种 eng
中图分类泌尿科学（泌尿生殖系疾病）;
关键词
Abiraterone acetate; Docetaxel; Elderly; Metastatic castration-resistant prostate cancer; Subsequent therapy; Treatment patterns;

机译：abiraTerone醋酸盐;多西紫杉醇;老年人;转移性阉割的前列腺癌;随后的治疗;治疗模式;

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1. Subsequent Chemotherapy and Treatment Patterns After Abiraterone Acetate in Patients with Metastatic Castration-resistant Prostate Cancer: Post Hoc Analysis of COU-AA-302 [J] . de Bono Johann S., Smith Matthew R., Saad Fred, European urology . 2017,第4期

机译：转移阉割前列腺癌患者乙酸乙酯后的后续化疗和治疗模式：CO-AA-302后HOC分析
2. Re: Johann S. de Bono, Matthew R. Smith, Fred Saad, et al. Subsequent Chemotherapy and Treatment Patterns After Abiraterone Acetate in Patients with Metastatic Castration-resistant Prostate Cancer: Post Hoc Analysis of COU-AA-302. Eur Urol. In press. http://dx.doi.org/10.1016/j.eururo.2016.06.033 [J] . Roviello Giandomenico, Generali Daniele, Petrioli Roberto European urology . 2017,第2期

机译：Re：Johann S. de Bono，Matthew R. Smith，Fred Saad等人。后续化疗和治疗模式在转移阉割前列腺癌患者乙酸盐后：CO-AA-302后HOC分析。 EUR UROL。在新闻。 http://dx.doi.org/10.1016/j.eururo.2016.06.033
3. Impact of Bone-targeted Therapies in Chemotherapy-naive Metastatic Castration-resistant Prostate Cancer Patients Treated with Abiraterone Acetate: Post Hoc Analysis of Study COU-AA-302 [J] . Saad Fred, Shore Neal, Van Poppel Hendrik, European urology . 2015,第4期

机译：骨靶向疗法对醋酸阿比特龙治疗的初治转移性去势抵抗性前列腺癌患者的影响：研究COU-AA-302的事后分析
4. Metastatic Hormone-Sensitive and Castration-Resistant Prostate Cancer: A Decade of Progress and Ongoing Discoveries [C] . Leonel Hernez-Aya, Maha Hussain Genitourinary Cancers Symposium. . 2014

机译：转移激素敏感和阉割的前列腺癌：进步和持续发现的十年
5. Muscle Cross-Sectional Area Is Improved and Physical Funciton Is Maintained After Home-Based Exercise in Men with Metastatic Castration-Resistant Prostate Cancer Undergoing Androgen Deprivation Therapy [D] . Alzer, Mohamdod Saber. 2020

机译：改善肌横截面积，并且在具有转移阉割的前列腺癌接受雄激素剥夺治疗的男性中的男性锻炼之后，将物理静脉凝集维持
6. Subsequent Chemotherapy and Treatment Patterns After Abiraterone Acetate in Patients with Metastatic Castration-resistant Prostate Cancer: Post Hoc Analysis of COU-AA-302 [O] . Johann S. de Bono, Matthew R. Smith, Fred Saad, -1

机译：醋酸阿比特龙治疗转移性去势抵抗性前列腺癌患者的后续化疗和治疗方式：COU-AA-302事后分析
7. Subsequent Chemotherapy and Treatment Patterns After Abiraterone Acetate in Patients with Metastatic Castration-resistant Prostate Cancer: Post Hoc Analysis of COU-AA-302 [O] . de Bono Johann S., Smith Matthew R., Saad Fred, 2016

机译：醋酸阿比特龙治疗转移性去势抵抗性前列腺癌患者的后续化疗和治疗方式：COU-AA-302事后分析

Subsequent Chemotherapy and Treatment Patterns After Abiraterone Acetate in Patients with Metastatic Castration-resistant Prostate Cancer: Post Hoc Analysis of COU-AA-302

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