Factors influencing the perception of protective isolation in patients undergoing haematopoietic stem cell transplantation: A multicentre prospective study

摘要

Abstract Objectives To identify which factors can influence the patients’ perception of protective isolation following Haematopoietic Stem Cell Transplantation (HSCT). Methods This is a prospective study conducted in 10 Italian centres, members of the Italian Group of stem cell transplant (GITMO). Patients’ perception of protective isolation was assessed using the ISOLA scale between 7 and 9?days post‐transplant. Statistical linear regression analysis was performed. Results The participants were 182 adult patients receiving autologous (48%) or allogeneic (52%) HSCT in protective isolation. Male sex ( β ?=?.152), education level ( β ?=??.245), double room ( β ?=?.186), satisfaction with visiting hours ( β ?=??.174) and emotional support from nurses ( β ?=??.169) were independently associated with isolation‐related suffering . Significant predictors of the relationship with oneself included body temperature ( β ?=??.179), fatigue ( β ?=??.192) and emotional support from nurses ( β ?=??.292). Factors independently associated with the relationship with others were education ( β ?=??.230), chemotherapy cycles ( β ?=??.218), pain ( β ?=?.150) and satisfaction with visiting hours ( β ?=??.162). Conclusion Healthcare providers should pay greater attention in caring for those patients who are at risk for a negative isolation experience. Nurses should provide emotional support.