Development and validation of the first HPLC method for quantification of perampanel and stiripentol in mouse matrices using an innovator salting-out assisted liquid-liquid extraction procedure optimized by a design of experiments approach

Alves Gilberto; Meirinho Sara; Campos Goncalo; Fortuna Ana; Falcao Amilcar; Rodrigues Marcio

首页> 外文期刊>European journal of clinical investigation >Development and validation of the first HPLC method for quantification of perampanel and stiripentol in mouse matrices using an innovator salting-out assisted liquid-liquid extraction procedure optimized by a design of experiments approach

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Development and validation of the first HPLC method for quantification of perampanel and stiripentol in mouse matrices using an innovator salting-out assisted liquid-liquid extraction procedure optimized by a design of experiments approach

机译：采用实验方法设计优化的小鼠矩阵中Perampanel和甲烷酮在小鼠基质中定量综合酚和甘油醇的开发和验证

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来源
《European journal of clinical investigation》 |2019年第s1期|共1页
作者
Alves Gilberto; Meirinho Sara; Campos Goncalo; Fortuna Ana; Falcao Amilcar; Rodrigues Marcio;
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作者单位

Univ Beira Interior CICS UBI Hlth Sci Res Ctr Covilha Portugal;

Univ Beira Interior CICS UBI Hlth Sci Res Ctr Covilha Portugal;

Univ Beira Interior CICS UBI Hlth Sci Res Ctr Covilha Portugal;

Univ Coimbra CIBIT Coimbra Inst Biomed Imaging &

Translat Res Coimbra Portugal;

Univ Coimbra CIBIT Coimbra Inst Biomed Imaging &

Translat Res Coimbra Portugal;

Univ Beira Interior CICS UBI Hlth Sci Res Ctr Covilha Portugal;

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正文语种 eng
中图分类临床医学;
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1. Development and validation of the first HPLC method for quantification of perampanel and stiripentol in mouse matrices using an innovator salting-out assisted liquid-liquid extraction procedure optimized by a design of experiments approach [J] . Alves Gilberto, Meirinho Sara, Campos Goncalo, European journal of clinical investigation . 2019,第S1期

机译：采用实验方法设计优化的小鼠矩阵中Perampanel和甲烷酮在小鼠基质中定量综合酚和甘油醇的开发和验证
2. Salting-Out Assisted Liquid-Liquid Extraction for Quantification of Febuxostat in Plasma Using RP-HPLC and Its Pharmacokinetic Application [J] . Tandel Devang, Shah Purvi, Patel Kalpana, Journal of Chromatographic Science . 2016,第10期

机译：使用RP-HPLC及其药代动力学应用，盐析辅助液液萃取在血浆中血糖溶液的定量
3. An automated salting-out assisted liquid-liquid microextraction approach using 1-octylamine: On-line separation of tetracycline in urine samples followed by HPLC-UV determination [J] . Cherkashina Ksenia, Vakh Christina, Lebedinets Sofya, Talanta: The International Journal of Pure and Applied Analytical Chemistry . 2018,第期

机译：使用1-辛基胺的自动腌制辅助液体微萃取方法：在尿液样品中的四环素在线分离，然后进行HPLC-UV测定
4. Development of Multi-Class, Multi-Residue UHPLC MS/MS Method for Screening/Quantification of Veterinary Drugs in Food Matrices and Related Products [C] . Azeem Hasan, Hui Zhao, John Zulkoski, ASMS Conference on Mass Spectrometry and Allied Topics . 2016

机译：用于筛选/定量食品基质和相关产品中兽医药物的多级多残基UHPLC MS / MS方法的研制
5. Part I. Evaluation of silver as a reductive amperometric detector electrode for HPLC and FIA. Part II. Evaluation of supercritical fluid extraction (SFE) as a sample preparation technique. Part III. Development and validation of HPLC methods using supercritical fluid extraction and reversed-phase HPLC with electrochemical detection (LCEC). [D] . Schneiderman, Martin Alan. 1990

机译：第一部分：银作为HPLC和FIA的还原型安培检测器电极的评估。第二部分评价超临界流体萃取（SFE）作为样品制备技术。第三部分使用超临界流体萃取和带电化学检测的反相HPLC（LCEC）的HPLC方法的开发和验证。
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机译：盐析辅助液 - 液萃取联合HPLC从环境水域进行量化提取痕量多标准农药残留量

Development and validation of the first HPLC method for quantification of perampanel and stiripentol in mouse matrices using an innovator salting-out assisted liquid-liquid extraction procedure optimized by a design of experiments approach

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