Inter-heterogeneity and intra-heterogeneity of alpha(v)beta(3) in non-small cell lung cancer and small cell lung cancer patients as revealed by Ga-68-RGD2 PET imaging

Kang Fei; Wang Zhe; Li Guoquan; Wang Shengjun; Liu Daliang; Zhang Mingru; Zhao Mingxuan; Yang Weidong; Wang Jing

首页> 外文期刊>European Journal of Nuclear Medicine and Molecular Imaging >Inter-heterogeneity and intra-heterogeneity of alpha(v)beta(3) in non-small cell lung cancer and small cell lung cancer patients as revealed by Ga-68-RGD2 PET imaging

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Inter-heterogeneity and intra-heterogeneity of alpha(v)beta(3) in non-small cell lung cancer and small cell lung cancer patients as revealed by Ga-68-RGD2 PET imaging

机译：非小细胞肺癌和小型细胞肺癌患者的α（v）β（3）的异质性和异质性，如GA-68-RGD2宠物成像所透露的

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Purpose Integrin alpha(v)beta(3) is the therapeutic target of the antiangiogenic drug cilengitide. The objective of this study was to compare alpha(v)beta(3) levels in non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC) patients, by using the positron emission tomography (PET) tracer Ga-68-labeled dimerized-RGD (Ga-68-RGD2).

机译：目的，整合蛋白α（v）β（3）是抗血管生成药物食指的治疗靶标。本研究的目的是通过使用正电子发射断层扫描（PET）示踪GA-68，将非小细胞肺癌（NSCLC）和小细胞肺癌（SCLC）患者的α（v）β（3）水平进行比较 - 标记的二聚化-RGD（GA-68-RGD2）。

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来源
《European Journal of Nuclear Medicine and Molecular Imaging》 |2017年第9期|共9页
作者
Kang Fei; Wang Zhe; Li Guoquan; Wang Shengjun; Liu Daliang; Zhang Mingru; Zhao Mingxuan; Yang Weidong; Wang Jing;
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作者单位

Fourth Mil Med Univ Xijing Hosp Dept Nucl Med 127 West Changle Rd Xian Peoples R China;

Fourth Mil Med Univ Xijing Hosp Dept Nucl Med 127 West Changle Rd Xian Peoples R China;

Fourth Mil Med Univ Xijing Hosp Dept Nucl Med 127 West Changle Rd Xian Peoples R China;

Fourth Mil Med Univ Xijing Hosp Dept Nucl Med 127 West Changle Rd Xian Peoples R China;

Fourth Mil Med Univ Xijing Hosp Dept Nucl Med 127 West Changle Rd Xian Peoples R China;

Fourth Mil Med Univ Xijing Hosp Dept Nucl Med 127 West Changle Rd Xian Peoples R China;

Fourth Mil Med Univ Xijing Hosp Dept Nucl Med 127 West Changle Rd Xian Peoples R China;

Fourth Mil Med Univ Xijing Hosp Dept Nucl Med 127 West Changle Rd Xian Peoples R China;

Fourth Mil Med Univ Xijing Hosp Dept Nucl Med 127 West Changle Rd Xian Peoples R China;

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原文格式 PDF
正文语种 eng
中图分类放射医学;
关键词
Small cell lung cancer; Non-small cell lung cancer; Integrin alpha(v)beta(3); Cilengitide; Ga-68-labeled dimerized-RGD;

机译：小细胞肺癌;非小细胞肺癌;整合蛋白α（v）β（3）;西兰德;Ga-68标记的二聚体-RGD;

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1. Inter-heterogeneity and intra-heterogeneity of alpha(v)beta(3) in non-small cell lung cancer and small cell lung cancer patients as revealed by Ga-68-RGD2 PET imaging [J] . Kang Fei, Wang Zhe, Li Guoquan, European Journal of Nuclear Medicine and Molecular Imaging . 2017,第9期

机译：非小细胞肺癌和小型细胞肺癌患者的α（v）β（3）的异质性和异质性，如GA-68-RGD2宠物成像所透露的
2. FDG-PET scan in potentially operable non-small cell lung cancer: do anatometabolic PET-CT fusion images improve the localisation of regional lymph node metastases? The Leuven Lung Cancer Group. [J] . Vansteenkiste JF, Stroobants SG, Dupont PJ, European journal of nuclear medicine . 1998,第11期

机译：潜在可手术的非小细胞肺癌的FDG-PET扫描：解剖代谢PET-CT融合图像能否改善局部淋巴结转移的定位？鲁汶肺癌小组。
3. SMAD6 contributes to patient survival in non-small cell lung cancer and its knockdown reestablishes TGF-beta homeostasis in lung cancer cells. [J] . Jeon HS, Dracheva T, Yang SH, Cancer research: The official organ of the American Association for Cancer Research, Inc . 2008,第23期

机译：SMAD6有助于非小细胞肺癌患者的生存，其敲低可重新建立肺癌细胞中的TGF-β动态平衡。
4. Lung Tumor Segmentation using Coupling-Net with Shape-focused Prior on Chest CT Images of Non-small Cell Lung Cancer Patients [C] . Sohyun Byun, Julip Jung, Helen Hong, Medical Imaging Conference . 2020

机译：非小细胞肺癌患者胸部CT图像上的形状聚焦先验耦合网络联合肺肿瘤分割
5. The cost effectiveness of screening for early stage lung cancer and the testing and treatment of molecular subgroups among non-small cell lung cancer patients in the province of ontario, canada [D] . Thao, Mallory. 2014

机译：加拿大安大略省非小细胞肺癌患者早期肺癌筛查的成本效益及分子亚群的检测和治疗
6. Respiration-Averaged CT for Attenuation Correction of PET Images – Impact on PET Texture Features in Non-Small Cell Lung Cancer Patients [O] . Nai-Ming Cheng, Yu-Hua Dean Fang, Din-Li Tsan, -1

机译：呼吸平均CT对PET图像的衰减校正–对非小细胞肺癌患者PET纹理特征的影响
7. Integrins .ALPHA.2.BETA.1, .ALPHA.5.BETA.1 and .ALPHA.v.BETA.5 Are Related to Tumor Growth and Metastasis of Non-small Cell Lung Cancer. [O] . Tatsuya Yoshimasu, Nariaki Matsuura, Ichiro Ota, 2001

机译：整合素.Alpha.2.beta.1，.alpha.5.beta.1和.alpha.v.beta.5与非小细胞肺癌的肿瘤生长和转移有关。

Inter-heterogeneity and intra-heterogeneity of alpha(v)beta(3) in non-small cell lung cancer and small cell lung cancer patients as revealed by Ga-68-RGD2 PET imaging

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