Sex differences in [C-11]ABP688 binding: a positron emission tomography study of mGlu5 receptors

Smart Kelly; Cox Sylvia M. L.; Scala Stephanie G.; Tippler Maria; Jaworska Natalia; Boivin Michel; Seguin Jean R.; Benkelfat Chawki; Leyton Marco

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Sex differences in [C-11]ABP688 binding: a positron emission tomography study of mGlu5 receptors

机译：[C-11] ABP688绑定性差异：MGLU5受体的正电子发射断层扫描研究

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Purpose The purpose of this study was to assess, in a large sample of healthy young adults, sex differences in the binding potential of [C-11]ABP688, a positron emission tomography (PET) tracer selective for the metabotropic glutamate type 5 (mGlu5) receptor.

机译：目的本研究的目的是评估，在大型健康年轻人样本中，性差异在[C-11] ABP688的结合潜力，正电子发射断层扫描（PET）示踪剂对代谢抑制型型5型（MGLU5 ）受体。

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来源
《European Journal of Nuclear Medicine and Molecular Imaging》 |2019年第5期|共5页
作者
Smart Kelly; Cox Sylvia M. L.; Scala Stephanie G.; Tippler Maria; Jaworska Natalia; Boivin Michel; Seguin Jean R.; Benkelfat Chawki; Leyton Marco;
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作者单位

McGill Univ Dept Psychiat 1033 Pine Ave West Montreal PQ H3A 1A1 Canada;

McGill Univ Dept Psychiat 1033 Pine Ave West Montreal PQ H3A 1A1 Canada;

McGill Univ Dept Psychiat 1033 Pine Ave West Montreal PQ H3A 1A1 Canada;

McGill Univ Dept Psychiat 1033 Pine Ave West Montreal PQ H3A 1A1 Canada;

Univ Ottawa Dept Cellular &

Mol Med Ottawa ON K1H 8M5 Canada;

Univ Laval Dept Psychol Quebec City PQ G1V 0A6 Canada;

CHU Ste Justine Res Ctr Montreal PQ H3T 1C5 Canada;

McGill Univ Dept Psychiat 1033 Pine Ave West Montreal PQ H3A 1A1 Canada;

McGill Univ Dept Psychiat 1033 Pine Ave West Montreal PQ H3A 1A1 Canada;

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原文格式 PDF
正文语种 eng
中图分类放射医学;
关键词
Metabotropic glutamate receptors; mGluR5; PET; Gender;

机译：代谢谷氨酸受体;mglur5;宠物;性别;

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专利

1. Sex differences in [C-11]ABP688 binding: a positron emission tomography study of mGlu5 receptors [J] . Smart Kelly, Cox Sylvia M. L., Scala Stephanie G., European Journal of Nuclear Medicine and Molecular Imaging . 2019,第5期

机译：[C-11] ABP688绑定性差异：MGLU5受体的正电子发射断层扫描研究
2. Marked global reduction in mGluR5 receptor binding in smokers and ex-smokers determined by [~（11）C]ABP688 positron emission tomography [J] . Funda Akkus, Simon M. Ametamey, Valerie Treyer, Proceedings of the National Academy of Sciences of the United States of America . 2013,第2期

机译：[〜（11）C] ABP688正电子发射断层扫描测定吸烟者和前吸烟者中mGluR5受体结合的总体减少
3. In vivo positron emission tomography imaging with ((1)(1)C)ABP688: binding variability and specificity for the metabotropic glutamate receptor subtype 5 in baboons. [J] . DeLorenzo C, Milak MS, Brennan KG, European Journal of Nuclear Medicine and Molecular Imaging . 2011,第6期

机译：（（1）（1）C）ABP688的体内正电子发射断层显像：狒狒中代谢型谷氨酸受体亚型5的结合变异性和特异性。
4. Kinetic modelling of receptor-ligand binding applied to positron emission tomographic studies [C] . Mary Jean Holland IFAC symposium on modelling and control in biomedical systems . 1997

机译：受体-配体结合的动力学模型应用于正电子发射断层扫描研究
5. Synthesis and positron emission tomography studies of radioligands targeting α7 nicotinic acetylcholine receptors in the central nervous system [D] . Kim, Sung Won 2007

机译：中枢神经系统中靶向α7烟碱乙酰胆碱受体的放射性配体的合成和正电子发射断层扫描研究
6. Sex differences in 11CABP688 binding: a positron emission tomography study of mGlu5 receptors [O] . Kelly Smart, Sylvia M. L. Cox, Stephanie G. Scala, -1

机译：11C ABP688结合中的性别差异：mGlu5受体的正电子发射断层扫描研究
7. Marked global reduction in mGluR5 receptor binding in smokers and ex-smokers determined by [11C]ABP688 positron emission tomography [O] . Akkus, Funda, Ametamey, Simon M, Treyer, Valerie, 2013

机译：通过[11C] ABP688正电子发射断层扫描确定吸烟者和前吸烟者中mGluR5受体结合的总体减少
8. Central Adrenergic Receptors as Mediators of Central Response to Stress: Study with Positron Emission Tomography (PET) [R] . Goffinet, A. M. 1988

机译：中枢肾上腺素受体作为中枢应激反应的介质：正电子发射断层扫描（pET）研究

Sex differences in [C-11]ABP688 binding: a positron emission tomography study of mGlu5 receptors

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