Cerebrospinal fluid neurofilament light chain levels: marker of progression to generalized amyotrophic lateral sclerosis

Tortelli R.; Copetti M.; Ruggieri M.; Cortese R.; Capozzo R.; Leo A.; DErrico E.; Mastrapasqua M.; Zoccolella S.; Pellegrini F.; Simone I. L.; Logroscino G.

首页> 外文期刊>European journal of neurology: the official journal of the European Federation of Neurological Societies >Cerebrospinal fluid neurofilament light chain levels: marker of progression to generalized amyotrophic lateral sclerosis

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Cerebrospinal fluid neurofilament light chain levels: marker of progression to generalized amyotrophic lateral sclerosis

机译：脑脊髓液神经膜轻链水平：广义肌营养的侧面硬化的进展标记

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摘要

Background and purpose: To evaluate whether cerebrospinal fluid (CSF) neurofilament light chain (NFL) levels could predict the time to generalization (TTG) in amyotrophic lateral sclerosis (ALS).

机译：背景和目的：评估脑脊髓液（CSF）神经膜轻链（NFL）水平是否可以预测肌营养侧面硬化（ALS）中的泛化（TTG）的时间。

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来源
《European journal of neurology: the official journal of the European Federation of Neurological Societies》 |2015年第1期|共4页
作者
Tortelli R.; Copetti M.; Ruggieri M.; Cortese R.; Capozzo R.; Leo A.; DErrico E.; Mastrapasqua M.; Zoccolella S.; Pellegrini F.; Simone I. L.; Logroscino G.;
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作者单位

Univ Bari Dept Basic Med Sci Neurosci &

Sense Organs Bari Italy;

IRCCS Casa Sollievo Sofferenza Unit Biostat San Giovanni Rotondo Italy;

Univ Bari Dept Basic Med Sci Neurosci &

Sense Organs Bari Italy;

Univ Bari Dept Basic Med Sci Neurosci &

Sense Organs Bari Italy;

Univ Bari Dept Basic Med Sci Neurosci &

Sense Organs Bari Italy;

Univ Bari Dept Basic Med Sci Neurosci &

Sense Organs Bari Italy;

Univ Bari Dept Basic Med Sci Neurosci &

Sense Organs Bari Italy;

Univ Bari Dept Basic Med Sci Neurosci &

Sense Organs Bari Italy;

Univ Bari Dept Basic Med Sci Neurosci &

Sense Organs Bari Italy;

IRCCS Casa Sollievo Sofferenza Unit Biostat San Giovanni Rotondo Italy;

Univ Bari Dept Basic Med Sci Neurosci &

Sense Organs Bari Italy;

Univ Bari Dept Basic Med Sci Neurosci &

Sense Organs Bari Italy;

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原文格式 PDF
正文语种 eng
中图分类神经病学;
关键词
ALS; biomarkers; CSF;

机译：作为生物标志物;CSF;

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专利

1. Cerebrospinal fluid neurofilament light chain levels: marker of progression to generalized amyotrophic lateral sclerosis [J] . Tortelli R., Copetti M., Ruggieri M., European journal of neurology: the official journal of the European Federation of Neurological Societies . 2015,第1期

机译：脑脊液神经丝轻链水平：进展为广泛性肌萎缩性侧索硬化症的标志
2. Cerebrospinal fluid neurofilament light chain levels: marker of progression to generalized amyotrophic lateral sclerosis [J] . Tortelli R., Copetti M., Ruggieri M., European journal of neurology: the official journal of the European Federation of Neurological Societies . 2015,第1期

机译：脑脊髓液神经膜轻链水平：广义肌营养的侧面硬化的进展标记
3. Elevated cerebrospinal fluid neurofilament light levels in patients with amyotrophic lateral sclerosis: A possible marker of disease severity and progression [J] . TortelliR., RuggieriM., CorteseR., European journal of neurology: the official journal of the European Federation of Neurological Societies . 2012,第12期

机译：肌萎缩性侧索硬化患者脑脊液神经丝光水平升高：疾病严重程度和进展的可能标志
4. Proteomic analysis of cerebrospinal fluid and plasma in patients with Amyotrophic Lateral Sclerosis [C] . T. Nash, J. Beri, M. Bereman Annual conference of the International Society of Exposure Science . 2017

机译：肌萎缩性侧索硬化症患者脑脊液和血浆的蛋白质组学分析
5. Targeting Motor Neuron - Immune System Crosstalk to Modulate the Disease Progression in Amyotrophic Lateral Sclerosis Mouse Model [D] . Trolese, Maria Chiara. 2020

机译：靶向运动神经元 - 免疫系统串扰调节肌营养侧面硬化小鼠模型中的疾病进展
6. Cerebrospinal Fluid Neurofilament Light Chain (NfL) Predicts Disease Aggressiveness in Amyotrophic Lateral Sclerosis: An Application of the D50 Disease Progression Model [O] . Marie Dreger, Robert Steinbach, Nayana Gaur, 2021

机译：脑脊髓液神经膜轻链（NFL）预测肌营养侧面硬化症中的疾病侵袭性：D50疾病进展模型的应用
7. Serum neurofilament light chain levels as a marker of upper motor neuron degeneration in patients with Amyotrophic Lateral Sclerosis [O] . B. Gille, M. De Schaepdryver, J. Goossens, 2018

机译：血清神经膜轻链水平作为肌营养侧面硬化症患者的上运动神经元变性的标记

Cerebrospinal fluid neurofilament light chain levels: marker of progression to generalized amyotrophic lateral sclerosis

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