Bangladeshi children with acute diarrhoea show faecal microbiomes with increased        <i xmlns='http://www.wiley.com/namespaces/wiley'>StreptococcusStreptococcus        abundance, irrespective of diarrhoea aetiology

Kieser Silas; Sarker Shafiqul A.; Sakwinska Olga; Foata Francis; Sultana Shamima; Khan Zeenat; Islam Shoheb; Porta Nadine; Combremont Séverine; Betrisey Bertrand; Fournier Coralie; Charpagne Aline; Descombes Patrick; Mercenier Annick; Berger Bernard; Brüssow Harald

摘要

Summary > We report streptococcal dysbiosis in acute diarrhoea irrespective of aetiology. Compared with 20 healthy local controls, 71 Bangladeshi children hospitalized with acute diarrhoea (AD) of viral, mixed viral/bacterial, bacterial and unknown aetiology showed a significantly decreased bacterial diversity with loss of pathways characteristic for the healthy distal colon microbiome (mannan degradation, methylerythritol phosphate and thiamin biosynthesis), an increased proportion of faecal streptococci belonging to the Streptococcus bovis and Streptococcus salivarius species complexes, and an increased level of E. coli ‐associated virulence genes. No enteropathogens could be attributed to a subgroup of patients. Elevated lytic coliphage DNA was detected in 2 out of 5 investigated enteroaggregative E. coli (EAEC)‐infected patients. Streptococcal outgrowth in AD is discussed as a potential nutrient‐driven consequence of glucose provided with oral rehydration solution. </abstract> </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> <div class="translation abstracttxt"> <span class="zhankaihshouqi fivelineshidden" id="abstract"> <span>机译：</span><Abstract XMLNS =“http://www.wiley.com/namespaces/wiley”type =“main”xml：lang =“en”> <title type =“main”>摘要</ title> >我们报告急性腹泻中的链球菌消化不良，与病因无关。与20个健康的地方控制相比，71名孟加拉国儿童住院治疗病毒，混合病毒/细菌，细菌和未知病毒学，细菌多样性显着降低，具有健康远端结肠微生物组的途径特征（人类降解，甲醇纤维醇磷酸盐和硫胺生物合成），增加了属于链球菌BOVIS的粪便链球菌的比例增加唾液链球菌唾液和物种复合物，以及增加的 e。 COLI </ i> - 分配的毒力基因。没有肠脱硫可能归因于患者的亚组。在5个研究的肠道中的2个中检测到升高的裂解COOIPHAGE DNA。 COLI </ i>（EAEC） - 摄取的患者。 AD中的链球菌产物被讨论为具有口服补液溶液的葡萄糖的潜在营养驱动后果。 </ p> </ abstract> </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> </div> <div class="record"> <h2 class="all_title" id="enpatent33" >著录项</h2> <ul> <li> <span class="lefttit">来源</span> <div style="width: 86%;vertical-align: text-top;display: inline-block;"> <a href='/journal-foreign-22868/'>《Environmental microbiology》</a> <b style="margin: 0 2px;">|</b><span>2018年第6期</span><b style="margin: 0 2px;">|</b><span>共14页</span> </div> </li> <li> <div class="author"> <span class="lefttit">作者</span> <p id="fAuthorthree" class="threelineshidden zhankaihshouqi"> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Kieser Silas&option=202" target="_blank" rel="nofollow">Kieser Silas;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Sarker Shafiqul A.&option=202" target="_blank" rel="nofollow">Sarker Shafiqul A.;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Sakwinska Olga&option=202" target="_blank" rel="nofollow">Sakwinska Olga;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Foata Francis&option=202" target="_blank" rel="nofollow">Foata Francis;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Sultana Shamima&option=202" target="_blank" rel="nofollow">Sultana Shamima;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Khan Zeenat&option=202" target="_blank" rel="nofollow">Khan Zeenat;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Islam Shoheb&option=202" target="_blank" rel="nofollow">Islam Shoheb;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Porta Nadine&option=202" target="_blank" rel="nofollow">Porta Nadine;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Combremont Séverine&option=202" target="_blank" rel="nofollow">Combremont Séverine;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Betrisey Bertrand&option=202" target="_blank" rel="nofollow">Betrisey Bertrand;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Fournier Coralie&option=202" target="_blank" rel="nofollow">Fournier Coralie;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Charpagne Aline&option=202" target="_blank" rel="nofollow">Charpagne Aline;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Descombes Patrick&option=202" target="_blank" rel="nofollow">Descombes Patrick;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Mercenier Annick&option=202" target="_blank" rel="nofollow">Mercenier Annick;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Berger Bernard&option=202" target="_blank" rel="nofollow">Berger Bernard;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Brüssow Harald&option=202" target="_blank" rel="nofollow">Brüssow Harald;</a> </p> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zkzz" style="display: none;">展开▼</span> </div> </li> <li> <div style="display: flex;"> <span class="lefttit">作者单位</span> <div style="position: relative;margin-left: 3px;max-width: 639px;"> <div class="threelineshidden zhankaihshouqi" id="fOrgthree"> <p>Gut Ecosystem DepartmentInstitute of Nutritional Science Nestlé Research Centre Vers‐chez‐les‐Blanc CH‐1000Lausanne 26 Switzerland;</p> <p>International Centre for Diarrheal Diseases Research Bangladesh (icddr b) Nutrition and Clinical Services Division 68 Shaheed Tajuddin Ahmed SharaniMohakhali Dhaka 1212 Bangladesh;</p> <p>Gut Ecosystem DepartmentInstitute of Nutritional Science Nestlé Research Centre Vers‐chez‐les‐Blanc CH‐1000Lausanne 26 Switzerland;</p> <p>Gut Ecosystem DepartmentInstitute of Nutritional Science Nestlé Research Centre Vers‐chez‐les‐Blanc CH‐1000Lausanne 26 Switzerland;</p> <p>International Centre for Diarrheal Diseases Research Bangladesh (icddr b) Nutrition and Clinical Services Division 68 Shaheed Tajuddin Ahmed SharaniMohakhali Dhaka 1212 Bangladesh;</p> <p>International Centre for Diarrheal Diseases Research Bangladesh (icddr b) Nutrition and Clinical Services Division 68 Shaheed Tajuddin Ahmed SharaniMohakhali Dhaka 1212 Bangladesh;</p> <p>International Centre for Diarrheal Diseases Research Bangladesh (icddr b) Nutrition and Clinical Services Division 68 Shaheed Tajuddin Ahmed SharaniMohakhali Dhaka 1212 Bangladesh;</p> <p>Gut Ecosystem DepartmentInstitute of Nutritional Science Nestlé Research Centre Vers‐chez‐les‐Blanc CH‐1000Lausanne 26 Switzerland;</p> <p>Gut Ecosystem DepartmentInstitute of Nutritional Science Nestlé Research Centre Vers‐chez‐les‐Blanc CH‐1000Lausanne 26 Switzerland;</p> <p>Nestlé Institute of Health Sciences EPFL Innovation ParkCH‐1015 Lausanne Switzerland;</p> <p>Nestlé Institute of Health Sciences EPFL Innovation ParkCH‐1015 Lausanne Switzerland;</p> <p>Nestlé Institute of Health Sciences EPFL Innovation ParkCH‐1015 Lausanne Switzerland;</p> <p>Nestlé Institute of Health Sciences EPFL Innovation ParkCH‐1015 Lausanne Switzerland;</p> <p>Gut Ecosystem DepartmentInstitute of Nutritional Science Nestlé Research Centre Vers‐chez‐les‐Blanc CH‐1000Lausanne 26 Switzerland;</p> <p>Gut Ecosystem DepartmentInstitute of Nutritional Science Nestlé Research Centre Vers‐chez‐les‐Blanc CH‐1000Lausanne 26 Switzerland;</p> <p>Gut Ecosystem DepartmentInstitute of Nutritional Science Nestlé Research Centre Vers‐chez‐les‐Blanc CH‐1000Lausanne 26 Switzerland;</p> </div> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zhdw" style="display: none;">展开▼</span> </div> </div> </li> <li > <span class="lefttit">收录信息</span> <span style="width: 86%;vertical-align: text-top;display: inline-block;"></span> </li> <li> <span class="lefttit">原文格式</span> <span>PDF</span> </li> <li> <span class="lefttit">正文语种</span> <span>eng</span> </li> <li> <span class="lefttit">中图分类</span> <span><a href="https://www.zhangqiaokeyan.com/clc/183.html" title="微生物学">微生物学;</a></span> </li> <li class="antistop"> <span class="lefttit">关键词</span> <p style="width: 86%;vertical-align: text-top;"> </p> </li> </ul> </div> </div> <div class="literature cardcommon"> <div class="similarity "> <h3 class="all_title" 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Bangladeshi children with acute diarrhoea show faecal microbiomes with increased StreptococcusStreptococcus abundance, irrespective of diarrhoea aetiology

摘要