Flower-like Ni(II)-based Metal-organic Framework-decorated Ag Nanoparticles: Fabrication, Characterization and Electrochemical Detection of Glucose

摘要

Glucose concentration monitoring is important for the prevention, diagnosis and treatment of diabetes. In this work, a composite material of AgNPs/MOF-74(Ni) was prepared for electrochemical determination of glucose. AgNPs/MOF-74(Ni) was characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM) and X-ray photoelectron spectroscopy (XPS). The electrochemical properties of the glassy carbon electrodes modified with the AgNPs/MOF-74(Ni) composites were characterized by cyclic voltammetry (CV) and current-time curve (I-t curve) with three electrode system. The determination of glucose with the electrode modified by AgNPs/MOF-74(Ni) has a linear range of 0.01 similar to 4 mM with the correlation coefficient (R-2) of 0.994. The detection limit is 4.7 mu M (S/N=3) and the sensitivity is 1.29 mA . mM(-1) . cm(-2). In addition, this sensing system possesses reasonable reproducibility and stability. The good performance of electrochemical determination for glucose is attributed to the concerted effect of silver nanoparticles and MOF-74(Ni) on the promotion of glucose oxidation