In Transition

Stanley J.Ziemski

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In Transition

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Sliding into the back nine of life,I feel both a bit of melancholy and also a bit of elation.As I exit,"stage left," from the ILMA Board,and hopefully (in the relatively near future) from our family business,I look forward to new challenges,even though I struggle some with how best to step aside.

机译：滑入人生的后九岁，我既感到忧郁又感到愉悦。当我离开ILMA董事会“离开舞台”，并希望（在不久的将来）退出我们的家族企业时，我期待着新的挑战，即使我在如何最好地放弃方面也遇到了困难。

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《Compoundings》 |2006年第5期|共1页
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Stanley J.Ziemski;
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7. Figure 1: (A–C) Example of annotation of chromosome 3R region by transitional gamma. For a given Hi-C matrix of Schneider-2 cells (A), TAD segmentations (B) are calculated by Armatus for a set of gamma values (from 0 to 10, a step of 0.01). Each line in B represents a single TAD. Then gamma transitional (C) is calculated for each genomic region as the minimal value of gamma where the region becomes inter-TAD or TAD boundary. The blue line in C represents the transitional gamma value for each genomic bin. The plots (B) and (C) are limited by gamma 2 for better visualization, although they are continued to the value of 10. Asterisk (*) denotes the region with gamma transitional of 1.64, the minimal value of gamma, where the corresponding region transitions from TAD to inter-TAD. (D) The histogram of the target value transitional gamma for Schneider-2 cell line. Note the peak at 10. [O] . -1

机译：图1：（A-C）通过过渡γ染色体3R区域注释的例子。对于给定的Hi-C矩阵的Schneider-2细胞（A），TAD分段（B）通过ARMATUS计算一组γ值（从0到10，步骤为0.01）。 B中的每一线代表单个TAD。然后针对每个基因组区域计算γ过渡（C），作为该区域变为TAD或TAD边界的伽马的最小值。 C中的蓝线表示每个基因组箱的过渡伽马值。图（b）和（c）受γ2的限制，以便更好地可视化，尽管它们持续到10.星号（*）表示具有1.64的伽马过渡的区域，伽玛的最小值，相应的伽玛区域从TAD转换到TAD。（d）施导德-2细胞系的靶值过渡γ的直方图。请注意10峰值。

In Transition

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