Synthetic sgRNAs to Streamline CRISPR Gene Editing Workflows Introduced

摘要

Horizon Discovery Group plc has announced the addition of predesigned synthetic single guide RNA (sgRNA) to its product range. The sgRNAs, available individually or as library collections, expand the Company's Edit-R gene engineering platform which provides a convenient and accessible approach to successful CRISPR gene editing. Using synthetic sgRNAs enables researchers to achieve reliable gene knockouts in even complex, difficult-to-edit cell types and experimental models. The synthetic sgRNAs have been designed using Horizon's proprietary algorithm to maximise the likelihood of functionally knocking out the gene (s) of interest while minimising off-target effects.