Evaluation of PEG (Polyethylene Glycol) Accumulation and Vacuolation in Nonclinical Chronic Toxicology Studies of Pegvaliase (PEGylated Recombinant Phenylalanine Ammonia Lyase)

Corado C. R.; Oppeneer T.; Gershman A.; Chandra S.; Tomlinson M. J.; ONeill C.; Sullivan L.

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Evaluation of PEG (Polyethylene Glycol) Accumulation and Vacuolation in Nonclinical Chronic Toxicology Studies of Pegvaliase (PEGylated Recombinant Phenylalanine Ammonia Lyase)

机译：PEG（聚乙二醇）积聚和真空在PEGValialse的非临床慢性毒理学研究中的累积和真空 - PEDS

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来源
《International journal of toxicology》 |2019年第1期|共1页
作者
Corado C. R.; Oppeneer T.; Gershman A.; Chandra S.; Tomlinson M. J.; ONeill C.; Sullivan L.;
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作者单位

BioMarin Novato CA USA;

BioMarin Novato CA USA;

BioMarin Novato CA USA;

BioMarin Novato CA USA;

Nova Pathol Bellingham WA USA;

BioMarin Novato CA USA;

BioMarin Novato CA USA;

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正文语种 eng
中图分类毒物学（毒理学）;
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1. Evaluation of PEG (Polyethylene Glycol) Accumulation and Vacuolation in Nonclinical Chronic Toxicology Studies of Pegvaliase (PEGylated Recombinant Phenylalanine Ammonia Lyase) [J] . Corado C. R., Oppeneer T., Gershman A., International journal of toxicology . 2019,第1期

机译：PEG（聚乙二醇）积聚和真空在PEGValialse的非临床慢性毒理学研究中的累积和真空 - PEDS
2. Partial rescue of neuropathology in the murine model of PKU following administration of recombinant phenylalanine ammonia lyase (pegvaliase) [J] . Marc Goldfinger, William L. Zeile, Carley R. Corado, Molecular genetics and metabolism . 2017,第1a2期

机译：重组苯丙氨酸氨酶（PEGVALIBSE）施用后PKU小鼠模型中神经病理学的部分拯救
3. Development of Pegylated Forms of Recombinant Rhodosporidium toruloides Phenylalanine Ammonia-Lyase for the Treatment of Classical Phenylketonuria. [J] . Gamez A, Sarkissian CN, Wang L, Molecular therapy: the journal of the American Society of Gene Therapy . 2005,第6期

机译：聚乙二醇化形式的重组托氏假单胞菌苯丙氨酸氨解酶治疗经典苯丙酮尿症。
4. Response surface optimization of medium composition for phenylalanine ammonia lyase production by recombinant E. coli [C] . Jian-dong Cui, Yan Li 2008年生物质能源技术国际会议论文集 . 2008

机译：重组大肠杆菌生产苯丙氨酸氨裂合酶培养基组成的响应面优化
5. Evaluation of the purity of commercially available phenylalanine ammonia lyase and variables affecting its encapsulation efficiency in cellulose nitrate microcapsules. [D] . Khot, Anagha. 2005

机译：评估市售苯丙氨酸氨裂合酶的纯度以及影响其在硝酸纤维素微胶囊中封装效率的变量。
6. Preclinical evaluation of multiple species of PEGylated recombinant phenylalanine ammonia lyase for the treatment of phenylketonuria [O] . Christineh N. Sarkissian, Alejandra Gámez, Lin Wang, 2008

机译：多种聚乙二醇化重组苯丙氨酸氨裂解酶治疗苯丙酮尿症的临床前评价
7. Partial rescue of neuropathology in the murine model of PKU following administration of recombinant phenylalanine ammonia lyase (pegvaliase) [O] . King's College London, Institute of Psychiatry, Psychology & Neuroscience, Maurice Wohl Clinical Neuroscience Institute, 5 Cutcombe Road, London SE5 9RX, UK ( host institution ), Goldfinger, Marc ( author ), Zeile, William L. ( UF author ), 2017

机译：给予重组苯丙氨酸氨裂合酶（pegvaliase）后，在PKU鼠模型中部分恢复神经病理学

Evaluation of PEG (Polyethylene Glycol) Accumulation and Vacuolation in Nonclinical Chronic Toxicology Studies of Pegvaliase (PEGylated Recombinant Phenylalanine Ammonia Lyase)

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