Modification of p21 level and cell cycle distribution by 50 Hz magnetic fields in human SH-SY5Y neuroblastoma cells

Luukkonen Jukka; Hoyto Anne; Sokka Miiko; Liimatainen Anu; Syvaoja Juhani; Juutilainen Jukka; Naarala Jonne

首页> 外文期刊>International Journal of Radiation Biology: Covering the Physical, Chemical, Biological, and Medical Effects of Ionizing and Non-ionizing Radiations >Modification of p21 level and cell cycle distribution by 50 Hz magnetic fields in human SH-SY5Y neuroblastoma cells

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Modification of p21 level and cell cycle distribution by 50 Hz magnetic fields in human SH-SY5Y neuroblastoma cells

机译：50Hz磁场在人SH-SY5Y神经母细胞瘤细胞中改变P21水平和细胞周期分布

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Purpose: In our previous studies, exposure to extremely low frequency (ELF) magnetic fields (MF) altered responses to DNA damage caused by menadione. The aim of this study was to evaluate possible ELF MF induced changes in proteins involved in DNA damage responses and in cell cycle distribution.

机译：目的：在我们以前的研究中，暴露于极低的频率（ELF）磁场（MF）改变了对由植物模引起的DNA损伤的反应。本研究的目的是评估可能的ELF MF诱导的蛋白质中参与DNA损伤反应和细胞周期分布的蛋白质的变化。

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《International Journal of Radiation Biology: Covering the Physical, Chemical, Biological, and Medical Effects of Ionizing and Non-ionizing Radiations》 |2017年第2期|共9页
作者
Luukkonen Jukka; Hoyto Anne; Sokka Miiko; Liimatainen Anu; Syvaoja Juhani; Juutilainen Jukka; Naarala Jonne;
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作者单位

Univ Eastern Finland Dept Environm &

Biol Sci Kuopio Campus Yliopistonranta 1 POB 1627 FI-70211;

Univ Eastern Finland Dept Environm &

Biol Sci Kuopio Campus Yliopistonranta 1 POB 1627 FI-70211;

Univ Eastern Finland Dept Environm &

Biol Sci Joensuu Finland;

Univ Eastern Finland Dept Environm &

Biol Sci Kuopio Campus Yliopistonranta 1 POB 1627 FI-70211;

Univ Eastern Finland Inst Biomed Kuopio Finland;

Univ Eastern Finland Dept Environm &

Biol Sci Kuopio Campus Yliopistonranta 1 POB 1627 FI-70211;

Univ Eastern Finland Dept Environm &

Biol Sci Kuopio Campus Yliopistonranta 1 POB 1627 FI-70211;

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原文格式 PDF
正文语种 eng
中图分类放射医学;
关键词
Cell cycle; DNA damage response; extremely low frequency magnetic field; genotoxicity; immunoblotting;

机译：细胞周期;DNA损伤反应;极低的频率磁场;基因毒性;免疫印迹;

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1. Modification of p21 level and cell cycle distribution by 50 Hz magnetic fields in human SH-SY5Y neuroblastoma cells [J] . Luukkonen Jukka, Hoyto Anne, Sokka Miiko, International Journal of Radiation Biology: Covering the Physical, Chemical, Biological, and Medical Effects of Ionizing and Non-ionizing Radiations . 2017,第2期

机译：50Hz磁场在人SH-SY5Y神经母细胞瘤细胞中改变P21水平和细胞周期分布
2. Different profiles of the mRNA levels of DNA repair genes in MCF-7 and SH-SY5Y cells after treatment with combination of cisplatin, 50-Hz electromagnetic field and bleomycin [J] . Fatemeh Sanie-Jahromi, Mostafa Saadat Biomedicine & pharmacotherapy =: Biomedecine & pharmacotherapie . 2017,第期

机译：用顺铂，50-Hz电磁场和博莱霉素组合处理MCF-7和SH-SY5Y细胞中DNA修复基因的MRNA水平的不同谱
3. Alterations in the cell cycle and in the protein level of cyclin D1, p21~CIPI, and p16~INK4a after exposure to 50 Hz MF in human cells [J] . Sandra Lange, Doreen Richard, Torsten Viergutz, Radiation and Environmental Biophysics . 2002,第2期

机译：人体细胞暴露于50 Hz MF后细胞周期和细胞周期蛋白D1，p21〜CIPI和p16〜INK4a蛋白水平的变化
4. Biological effect of the 50 Hz Magnetic Field in a three-dimension (3D) in vitro experimental model of SH-SY5Y human neuroblastoma cells [C] . Claudia Consales, Alessio Butera, Mariateresa Mancuso, Joint Meeting of the Bioelectromagnetics Society and the European BioElectromagnetics Association . 2018

机译：SH-SY5Y人神经母细胞瘤细胞三维（3D）中的50Hz磁场的生物学效应
5. Exosomal proteome changes induced by human tau expression are modulated by the presence of the microtubule-binding domain and alternatively spliced exons 2-3 in SH-SY5Y neuroblastoma cells [D] . Aladwan, Mohammad Mahmoud. 2017

机译：SH-SY5Y神经母细胞瘤细胞中微管结合结构域的存在和其他剪接的外显子2-3的存在可以调节人tau表达诱导的外泌体蛋白质组变化
6. Pre-Exposure to 50 Hz Magnetic Fields Modifies Menadione-Induced Genotoxic Effects in Human SH-SY5Y Neuroblastoma Cells [O] . Jukka Luukkonen, Anu Liimatainen, Anne Höytö, 2011

机译：预先暴露于50 Hz磁场会修饰甲萘醌诱导的人SH-SY5Y神经母细胞瘤细胞的遗传毒性作用。
7. Pre-Exposure to 50 Hz Magnetic Fields Modifies Menadione-Induced Genotoxic Effects in Human SH-SY5Y Neuroblastoma Cells [O] . Luukkonen, Jukka, Liimatainen, Anu, Höytö, Anne, 2011

机译：预先暴露于50 Hz磁场会修饰甲萘醌诱导的人SH-SY5Y神经母细胞瘤细胞的遗传毒性作用。

Modification of p21 level and cell cycle distribution by 50 Hz magnetic fields in human SH-SY5Y neuroblastoma cells

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