Evaluation of prenatal corticosteroid use in spontaneous preterm labor in the Brazilian Multicenter Study on Preterm Birth ( <fc xmlns='http://www.wiley.com/namespaces/wiley'>EMIP</fc>EMIP )

Dias Tabata Z.; Passini Renato; Tedesco Ricardo P.; Lajos Giuliane J.; Rehder Patricia M.; Nomura Marcelo L.; Costa Maria L.; Oliveira Paulo F.; Sousa Maria H.; Cecatti Jose G.; the Brazilian Multicenter Study on Preterm Birth (EMIP) study group; Marba Sergio T.; Guinsburg Ruth; Martinez Francisco E.; Zotarelli Vilma; Gurgel Lucio T.; Feitosa Francisco E.; Chaves George N.; Porto Ana M.; Coutinho Isabela C.; Barbosa Lima Antonio C.; Melo Elias F.; Leite Débora F.; Amorim Melania M.; Melo Adriana S.O.; Melo Fabiana O.; Martins Marília G.; Nunes Marynea V.; Paiva Cláudio S.; Lima Moises D.; Freire Djacyr M.; Trist?o Edson G.; Nascimento Denis J.; Menezes Carlos A.; Aquino Marcelo; Vettorazzi Janete; Senger Cintia E.; Assump??o Augusta M.B.; Guedes Marcela A.F.; Moreira Maria E.L.; Borges Vera T.; Maia Filho Nelson L.; Mathias Jacinta P.; Souza Eduardo; Zamarian Ana C.P.; Quintana Silvana M.; Melli Patrícia P.S.; Lotufo Fátima A.; Uzilin Kaliane; Zanette Elvira A.; Andreucci Carla B.; Oliveira Tenilson A.; Oliveira Laércio R.; Santos Marcos A.N.; Sass Nelson; Silveira Mirian R.F.; Coutinho Pedro R.; Siqueira Luciana

摘要

Abstract <section numbered="no" xml:id="ijgo12297-sec-0001"> <title type="main">Objective >To evaluate prenatal corticosteroid use in women experiencing spontaneous preterm labor and preterm delivery. </section> <section numbered="no" xml:id="ijgo12297-sec-0002"> <title type="main">Methods > The present cross‐sectional multicenter study analyzed interview data from patients attending 20 hospitals in Brazil owing to preterm delivery between April 1, 2011 and July 30, 2012. Patients were stratified based on preterm delivery occurring before 34?weeks or at 34–36 +6 ?weeks of pregnancy, and the frequency of prenatal corticosteroid use at admission was compared. Prenatal corticosteroid use, sociodemographic data, obstetric characteristics, and neonatal outcomes were examined. </section> <section numbered="no" xml:id="ijgo12297-sec-0003"> <title type="main">Results > There were 1455 preterm deliveries included in the present study; 527 (36.2%) occurred before 34?weeks of pregnancy and prenatal corticosteroids were used in 285 (54.1%) of these pregnancies. Among neonates delivered at 32–33 +6 ?weeks, prenatal corticosteroid use was associated with lower pneumonia ( P= 0.026) and mortality ( P= 0.029) rates. Among neonates delivered at 34–36 +6 ?weeks, prenatal corticosteroid use was associated with longer neonatal hospital admission ( P 0.001), and an increased incidence of 5‐minute Apgar scores below 7 ( P= 0.010), endotracheal intubation ( P= 0.042), surfactant use ( P= 0.006), neonatal morbidities ( P= 0.048), respiratory distress ( P= 0.048), and intraventricular hemorrhage ( P= 0.023). </section> <section numbered="no" xml:id="ijgo12297-sec-0004"> <title type="main">Conclusion >Preterm labor and late preterm delivery were associated with worse neonatal outcomes following prenatal corticosteroids. This could reflect a sub‐optimal interval between administration and delivery. </section> </abstract> </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> <div class="translation abstracttxt"> <span class="zhankaihshouqi fivelineshidden" id="abstract"> <span>机译：</span><Abstract XMLNS =“http://www.wiley.com/namespaces/wiley”type =“main”xml：id =“ijgo12297-abs-abs-abs-0001”> <标题类型=“main”>抽象</ title> <编号为=“否”XML：ID =“IJGo12297-SEC-0001”> <标题类型=“main”>目标</标题> >评估经历自发早产劳动和早产的女性的产前皮质类固醇。< / p> </ section> <sec numbyed =“no”xml：id =“ijgo12297-sec-0002”> <title type =“main”>方法</ title> >本横断面多中心研究分析在2011年4月1日至2012年7月30日期间在巴西参加巴西的患者采访数据。基于34〜34周或34-36个 +6 + 6 </ sup>之前，患者基于早产输送来分层怀孕的几周，比较了孕产阶级皮质类固醇用途的频率。检查产前皮质类固醇使用，社会渗透数据，产科特征和新生儿结果。 </ p> </ section> <secto numbyed =“no”xml：id =“ijgo12297-sec-0003”> <标题类型=“main”>结果</ title> >包含1455个早产本研究;在34个妊娠之前发生了527（36.2％），在这些怀孕中使用了产前皮质类固醇。在32-33 +6 </ sup>α的新生儿中，产前皮质类固醇用途与较低的肺炎（ p = </ i> 0.026）和死亡率（ p = </ i）有关。 > 0.029）速率。在34-36 +6 + 6 </ sup>α的新生儿中，产前皮质类固醇使用与较长的新生儿医院入院（ p＆ </ i> 0.001）相关，并且发病率5分钟APGAR分数低于7（ P = </ I> 0.010），气管插管（ P = </ I> 0.042），表面活性剂使用（ p = </ i> 0.006），新生儿病症（ p = </ i> 0.048），呼吸窘迫（ p = </ i> 0.048），腔内出血（ p = / i> 0.023）。 </ p> </ section> <sectoreded =“no”xml：id =“ijgo12297-sec-0004”> <标题类型=“main”>结论</ title> >早产和晚期早产与产前皮质类固醇后较差的新生儿结果相关。这可以反映给药和交付之间的次优隔。</ p> </ section> </ abstract> </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> </div> <div class="record"> <h2 class="all_title" id="enpatent33" >著录项</h2> <ul> <li> <span class="lefttit">来源</span> <div style="width: 86%;vertical-align: text-top;display: inline-block;"> <a href='/journal-foreign-21245/'>《International journal of gynecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics》</a> <b style="margin: 0 2px;">|</b><span>2017年第2期</span><b style="margin: 0 2px;">|</b><span>共8页</span> </div> </li> <li> <div class="author"> <span class="lefttit">作者</span> <p id="fAuthorthree" class="threelineshidden zhankaihshouqi"> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Dias Tabata Z.&option=202" target="_blank" rel="nofollow">Dias Tabata Z.;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Passini Renato&option=202" target="_blank" rel="nofollow">Passini Renato;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Tedesco Ricardo P.&option=202" target="_blank" rel="nofollow">Tedesco Ricardo P.;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Lajos Giuliane J.&option=202" target="_blank" rel="nofollow">Lajos Giuliane J.;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Rehder Patricia M.&option=202" target="_blank" rel="nofollow">Rehder Patricia M.;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Nomura Marcelo L.&option=202" target="_blank" rel="nofollow">Nomura Marcelo L.;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Costa Maria L.&option=202" target="_blank" rel="nofollow">Costa Maria L.;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Oliveira Paulo F.&option=202" target="_blank" rel="nofollow">Oliveira Paulo F.;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Sousa Maria H.&option=202" target="_blank" rel="nofollow">Sousa Maria H.;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Cecatti Jose G.&option=202" target="_blank" rel="nofollow">Cecatti Jose G.;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=the Brazilian Multicenter Study on Preterm Birth (EMIP) study group&option=202" target="_blank" rel="nofollow">the Brazilian Multicenter Study on Preterm Birth (EMIP) study group;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Marba Sergio T.&option=202" target="_blank" rel="nofollow">Marba Sergio T.;</a> <a 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style="display: flex;"> <span class="lefttit">作者单位</span> <div style="position: relative;margin-left: 3px;max-width: 639px;"> <div class="threelineshidden zhankaihshouqi" id="fOrgthree"> <p>Department of Obstetrics and GynecologyUniversity of CampinasCampinas Brazil;</p> <p>Department of Obstetrics and GynecologyUniversity of CampinasCampinas Brazil;</p> <p>Department of Obstetrics and GynecologyJundiaí Medical SchoolJundiaí Brazil;</p> <p>Department of Obstetrics and GynecologyUniversity of CampinasCampinas Brazil;</p> <p>Department of Obstetrics and GynecologyUniversity of CampinasCampinas Brazil;</p> <p>Department of Obstetrics and GynecologyUniversity of CampinasCampinas Brazil;</p> <p>Department of Obstetrics and GynecologyUniversity of CampinasCampinas Brazil;</p> <p>Unit of StatisticsUniversity of CampinasCampinas Brazil;</p> <p>Unit of StatisticsJundiaí Medical SchoolJundiaí Brazil;</p> <p>Department of Obstetrics and GynecologyUniversity of CampinasCampinas Brazil;</p> </div> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zhdw" style="display: none;">展开▼</span> </div> </div> </li> <li > <span class="lefttit">收录信息</span> <span style="width: 86%;vertical-align: text-top;display: inline-block;"></span> </li> <li> <span class="lefttit">原文格式</span> <span>PDF</span> </li> <li> <span class="lefttit">正文语种</span> <span>eng</span> </li> <li> <span class="lefttit">中图分类</span> <span><a href="https://www.zhangqiaokeyan.com/clc/197.html" title="妇产科学">妇产科学;</a></span> </li> <li class="antistop"> <span class="lefttit">关键词</span> <p style="width: 86%;vertical-align: text-top;"> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Late preterm&option=203" rel="nofollow">Late preterm;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Neonatal outcomes&option=203" rel="nofollow">Neonatal outcomes;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Prenatal corticosteroid&option=203" rel="nofollow">Prenatal corticosteroid;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Preterm delivery&option=203" rel="nofollow">Preterm delivery;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Preterm labor&option=203" rel="nofollow">Preterm labor;</a> </p> <div class="translation"> 机译：晚期早产;新生儿结果;产前皮质类固醇;早产;早产; </div> </li> </ul> </div> </div> <div class="literature cardcommon"> <div class="similarity "> <h3 class="all_title" id="enpatent66">相似文献</h3> <div class="similaritytab clearfix"> <ul> <li class="active" >外文文献</li> <li >中文文献</li> </ul> </div> <div class="similarity_details"> <ul > <li> <div> <b>1. </b><a class="enjiyixqcontent" href="/journal-foreign-detail/0704023018445.html">Evaluation of prenatal corticosteroid use in spontaneous preterm labor in the Brazilian Multicenter Study on Preterm Birth ( <fc xmlns="http://www.wiley.com/namespaces/wiley">EMIP</fc>EMIP 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Evaluation of prenatal corticosteroid use in spontaneous preterm labor in the Brazilian Multicenter Study on Preterm Birth ( EMIPEMIP )

摘要